Congenital diaphragmatic hernia (CDH)

By Mayo Clinic Staff
March 01, 2023

Research

Mayo Clinic is a pioneer in fetal surgery advances, allowing for earlier intervention when congenital birth problems are diagnosed.

A key example is a clinical trial for prenatal surgery to promote lung growth before babies are born. The goal is to develop regenerative approaches to improve lung development and outcomes.

Mayo experts continue to actively study how to lower the risks of fetal surgery, improve surgical approaches, and improve outcomes for both mothers and children.

Publications

See a list of publications about congenital diaphragmatic hernia by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Adam MP, et al., eds. Congenital diaphragmatic hernia overview. In: GeneReviews. University of Washington, Seattle; 1993-2022. https://www.ncbi.nlm.nih.gov/books/NBK1116/. Accessed March 21, 2022.
  2. Kirby E, et al. Congenital diaphragmatic hernia: Current management strategies from antenatal diagnosis to long-term follow-up. Pediatric Surgery International. 2020; doi:10.1007/s00383-020-04625-z.
  3. Kolver ML, et al. Fetal intervention for congenital diaphragmatic hernia. Seminars in Pediatric Surgery. 2019; doi:10.1053/j.sempedsurg.2019.07.001.
  4. Cordier A-G, et al. Prenatal diagnosis, imaging, and prognosis in congenital diaphragmatic hernia. Seminars in Perinatology. 2020; doi:10.1053/j.semperi.2019.07.002.
  5. Basurto D, et al. Prenatal diagnosis and management of congenital diaphragmatic hernia. Best Practice & Research Clinical Obstetrics & Gynecology. 2019; doi:10.1016/j.bpobgyn.2018.12.010.
  6. Blumenfeld YJ, et al. New approaches to congenital diaphragmatic hernia. Current Opinion in Obstetrics & Gynecology. 2020; doi:10.1097/GCO.0000000000000615.
  7. Chatterjee D, et al. Update on congenital diaphragmatic hernia. Anesthesia & Analgesia. 2020; doi:0.1213/ANE.0000000000004324.
  8. Dingeldein M. Congenital diaphragmatic hernia: Management & outcomes. Advances in Pediatrics. 2018; doi:10.1016/j.yapd.2018.05.001.
  9. Bence CM, et al. Ex utero intrapartum treatment (EXIT) procedures. Seminars in Pediatric Surgery. 2019; doi:10.1053/j.sempedsurg.2019.07.003.
  10. Hollinger LE, et al. Long term follow-up in congenital diaphragmatic hernia. Seminars in Perinatology. 2020; doi:10.1053/j.semperi.2019.07.010.
  11. Deprest JA, et al. Randomized trial of fetal surgery for moderate left diaphragmatic hernia. New England Journal of Medicine. 2021; doi:10.1056/NEJMoa2026983.
  12. AskMayoExpert. Fetal endoscopic tracheal occlusion. Mayo Clinic; 2022.
  13. AskMayoExpert. Extracorporeal membrane oxygenation (ECMO). Mayo Clinic; 2022.
  14. Medical review (expert opinion). Mayo Clinic. March 21, 2022.
  15. American Pediatric Surgical Association. Prenatal counseling series: Congenital diaphragmatic hernia. https://apsapedsurg.org/resources/resources/prenatal-counseling-series/. Accessed March 17, 2022.