Common variable immunodeficiency is an immune system disorder that causes you to have low levels of the proteins that help fight infections. If you have this condition, you'll likely have repeated infections in your ears, sinuses, and respiratory system. You'll also have an increased risk of digestive disorders, blood disorders, and cancer. The condition can be inherited, or you can develop it during your lifetime.
Symptoms of common variable immunodeficiency may appear during childhood or adolescence, though many people don't experience them until adulthood. If you have this condition, you'll likely have repeated infections in your ears, sinuses, and respiratory system.
Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this disease.
Common variable immunodeficiency care at Mayo Clinic
Dec. 19, 2018
- National Library of Medicine. Common variable immune deficiency. Genetics Home Reference. https://ghr.nlm.nih.gov/condition/common-variable-immune-deficiency#synonyms. Accessed Feb. 1, 2017.
- Mason RJ, et al. Pulmonary complications of primary immunodeficiencies. In: Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, Pa.; Saunders Elsevier. 2016. http://www.clinicalkey.com. Accessed Feb. 1, 2017.
- Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Dec. 8, 2016.
Common variable immunodeficiency