Colon cancer screening: At what age can you stop?

By Mayo Clinic Staff
Dec. 24, 2025

I'm 76 years old and am wondering when it's no longer necessary to get colon cancer screening? Is there an upper age limit?

There's no upper age limit for colon cancer screening. But most medical organizations in the United States agree that the benefits of screening decline after age 75 for most people and there's little evidence to support continuing screening after age 85.

Discuss colon cancer screening with your health care provider. Together you can consider the benefits and risks of continued screening.

You and your provider might decide that it's a good idea to continue colon cancer screening if any of the following apply to you:

  • You're in excellent health.
  • You've never had colon cancer screening before.
  • You have a factor that increases your risk of colon cancer, such as a strong family history of colon cancer, a previous colon cancer diagnosis or a personal history of colon polyps.
  1. Colorectal cancer: Screening and management (adult). AskMayoExpert. Mayo Clinic; 2021.
  2. U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. JAMA. 2021; doi:10.1001/jama.2021.6238.
  3. Colorectal cancer screening. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=2&id=1429. Accessed Dec. 7, 2021.
  4. Wolf AMD, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA: A Cancer Journal for Clinicians. 2018; doi:10.3322/caac.21457.
  5. Shaukat A, et al. ACG clinical guideline: Colorectal cancer screening 2021. American Journal of Gastroenterology. 2021; doi:10.14309/ajg.0000000000001122.

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