Carcinoma of unknown primary

Dec. 04, 2024

Carcinoma of unknown primary care at Mayo Clinic

Mayo Clinic doctors work together to provide compassionate, comprehensive care for people with carcinoma of unknown primary. People with cancer receive care from the experts at Mayo Clinic Comprehensive Cancer Center.

Your Mayo Clinic care team

At Mayo Clinic, doctors work in multidisciplinary teams that take all of your health concerns into consideration. Your care team might include:

  • Medical oncologists.
  • Radiation oncologists.
  • Surgeons.
  • Radiologists.
  • Pathologists.
  • Other healthcare professionals, as needed.

Advanced diagnostic techniques

Mayo Clinic doctors have access to the latest technology to help them investigate where carcinoma of unknown primary began. Even when a primary site can't be determined, these tests give doctors clues that aid in selecting the best treatment.

Radiologists use advanced imaging technology to search for signs of cancer.

Pathologists have cutting-edge laboratory tests available to analyze cancer cells for clues about their origin. Doctors and hospitals around the world send biopsy samples to Mayo Clinic pathologists for evaluation.

Expertise and rankings

Mayo Clinic doctors are respected for their expertise in caring for people with carcinoma of unknown primary.

  • Collaboration. At Mayo Clinic, medical oncologists, radiation oncologists, surgeons, radiologists and pathologists work as a multidisciplinary team to provide comprehensive care to those with carcinoma of unknown primary. Other professionals are included as needed.
  • Experience. Mayo Clinic doctors have experience diagnosing and treating carcinoma of unknown primary. Each year they provide expert care to many people with this cancer.
  • Comprehensive cancer center. Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute-Designated Comprehensive Cancer Center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.
  1. DeVita VT Jr, et al., eds. Cancer of unknown primary. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Wolters Kluwer; 2023. Accessed Nov. 1, 2024.
  2. Carcinoma of unknown primary treatment (PDQ) – Patient version. National Cancer Institute. https://www.cancer.gov/types/unknown-primary/patient/unknown-primary-treatment-pdq. Accessed Nov. 1, 2024.
  3. Occult primary (cancer of unknown primary [CUP]). Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1451. Accessed Nov. 1, 2024.
  4. Niederhuber JE, et al., eds. Carcinoma of unknown primary. In: Abeloff's Clinical Oncology. 6th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Nov. 1, 2024.
  5. Palliative care. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=3&id=1454. Accessed Nov. 1, 2024.
  6. Distress management. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=3&id=1431. Accessed Nov. 5, 2024.