Barrett's esophagus

Oct. 07, 2026

Barrett's esophagus care at Mayo Clinic

Your Mayo Clinic care team

At Mayo Clinic, a team of experts in several specialties — including digestive diseases, throat diseases and surgery — care for people with Barrett's esophagus. Working as a team, doctors are able to provide comprehensive diagnosis and treatment plans that are tailored to your needs.

Advanced diagnosis and treatment

Mayo Clinic researchers are working to improve the diagnosis and treatment of Barrett's esophagus. Specific efforts involve:

  • Novel imaging techniques to detect precancerous changes that may indicate early cancer changes in Barrett's esophagus.
  • Advanced endoscopy to treat Barrett's esophagus and early cancers.
  • Medications that can decrease cancer risk.
  • Genetic factors that may be related to Barrett's esophagus.

Mayo Clinic offers several nonsurgical treatment options for Barrett's esophagus. For many people, these minimally invasive treatments can eliminate disease without the need for surgery. If you need surgery, Mayo specialists use a minimally invasive approach.

Expertise and rankings

Experience

Mayo Clinic doctors care for more than 4,100 people with Barrett's esophagus each year.

Research leaders

The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry compiles information from people receiving care at Mayo. Researchers hope this information can help them gain a greater understanding of the genetic basis of Barrett's esophagus. This work may lead to a genetic blood test to screen for the disease. Mayo specialists also are studying the use of genetic information to determine which treatments are likely to offer the best results for people with Barrett's esophagus.

Mayo Clinic specialists are part of the American Gastroenterological Association Barrett's esophagus guideline writing team.

Nationally recognized expertise

  1. Qumseya B, et al. ASGE guideline on screening and surveillance of Barrett esophagus. Gastrointestinal Endoscopy. 2019; doi:10.1016/j.gie.2019.05.012.
  2. Barrett's's esophagus. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/digestive-diseases/Barrett'ss-esophagus. Accessed Feb. 5, 2026.
  3. Spechler SJ. Barrett's esophagus: Epidemiology, clinical manifestations, and diagnosis. https://www.uptodate.com/contents/search. Accessed Feb. 5, 2026.
  4. Acid reflux (GER & GERD) in adults. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/digestive-diseases/acid-reflux-ger-gerd-adults/all-content. Accessed Feb. 5, 2026.
  5. Shaheen NJ, et al. Diagnosis and management of Barrett's esophagus: An updated ACG guideline. 2022; doi:10.14309/ajg.0000000000001680.
  6. AskMayoExpert. Barrett esophagus. Mayo Clinic; 2023.
  7. Spechler SJ, et al. Barrett's esophagus: Surveillance and management. https://www.uptodate.com/contents/search. Accessed Feb. 5, 2026.
  8. Ami TR. Allscripts EPSi. Mayo Clinic. April 17, 2024.