Anal cancer

By Mayo Clinic Staff
Feb. 04, 2026

Research

Mayo Clinic doctors and researchers are studying the latest in the diagnosis and treatment of anal cancer.

Mayo Clinic Comprehensive Cancer Center meets the strict standards for a U.S. National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about anal cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Anal carcinoma. National Comprehensive Cancer Network. https://www.nccn.org/patientresources/patient-resources/guidelines-for-patients/guidelines-for-patients-details?patientGuidelineId=58. Accessed Nov. 17, 2025.
  2. Palliative care. National Comprehensive Cancer Network. https://www.nccn.org/patientresources/patient-resources/guidelines-for-patients/guidelines-for-patients-details?patientGuidelineId=73. Accessed Nov. 17, 2025.
  3. Anal cancer treatment (PDQ)— Health professional version. National Cancer Institute. https://www.cancer.gov/types/anal/hp/anal-treatment-pdq. Accessed Nov. 17, 2025.
  4. Gowin K, et al. Integrative therapies in cancer care: An update on the guidelines. American Society of Clinical Oncology Education Book. 2024; doi:10.1200/EDBK_431554.
  5. American College of Surgeons. Anus: Protocol for cancer staging documentation. In: AJCC Cancer Staging System. American College of Surgeons; 2025. https://www.facs.org/quality-programs/cancer-programs/american-joint-committee-on-cancer/version-9/. Accessed Nov. 18, 2025.
  6. Warner KJ. Allscripts EPSi. Mayo Clinic. May 7, 2019.
  7. Cancer stat facts: Anal cancer. National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) Program. https://seer.cancer.gov/statfacts/html/anus.htmlAccessed Dec. 22, 2025.
  8. Morris VK, et al. Systemic therapy for stage I-III anal squamous cell carcinoma: ASCO guideline. Journal of Clinical Oncology. 2025; doi:10.1200/JCO-24-02120. Accessed Nov. 18, 2025.
  9. Willett CG, et al. Clinical presentation, diagnosis, and staging of anal cancer. https://www.uptodate.com/contents/search. Accessed Nov. 18, 2025.
  10. DeVita VT Jr, et al., eds. Cancer of the anal region. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. ProQuest Ebook Central. Wolters Kluwer; 2023. Accessed Nov. 18, 2025.
  11. AskMayoExpert. Anal cancer (adult). Mayo Clinic; 2024.