Residential Treatment Program in Minnesota

The four-day residential treatment program at the Nicotine Dependence Center on Mayo Clinic's campus in Minnesota provides the most intensive treatment option available for stopping smoking. More than 1,300 people have been treated since the program began in 1992.


The residential program offers:

  • A secure, tobacco-free setting
  • Individual and group counseling
  • Medications to relieve withdrawal symptoms
  • Doctor-supervised care
  • Long-term follow-up to prevent relapse


What to expect

The program lasts four days, from Monday to Thursday, and is based on principles of addiction therapy and behavior change. Sessions are kept small, with a maximum of 11 participants, to ensure that each person's needs are met. You are assigned an individual counselor who is certified as a tobacco treatment specialist. An internal medicine doctor oversees your care.

Services include medical assessment and daily medical follow-up, individual and group counseling, educational sessions to help with stress management, relapse prevention, wellness coaching, tobacco-related health education, and sessions to assist family members and significant others in helping in the recovery process.

The program is staffed 24 hours a day. Staff members follow up regularly with all program participants to help prevent relapse. More than 52 percent of participants report being smoke-free six months after completing the program.

Program dates | Program costs | Program guidelines

Registration requests

To submit a registration request for the Residential Treatment Program, you may use the online appointment request form or contact the Nicotine Dependence Center by phone or email.

Contact us

  • 507-266-9392
  • 800-344-5984 (toll-free)

Mailing address:

  • Nicotine Dependence Center
  • Four-Day Residential Treatment Program
  • Mayo Clinic
  • Colonial Building, Third Floor
  • 200 First St. SW
  • Rochester, MN 55905