Elizabeth A. Coon, M.D.

  1. Neurologist
  1. Cunningham R, Badihian N, Chou C, Jackson L, Rhee L, Coon E. Neuropalliative Care Symptoms and Distress in Patients with Multiple System Atrophy (P1-7.001). Neurology. 2025 Apr 8; 104 (7_Supplement_1):1719 Epub 2025 Apr 07
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  2. Coon EA, Badihian N, McCarter SJ, Sletten DM, Berini SE, Benarroch EE, Sandroni P, Low PA, Singer W. The phenotype of "pure" autonomic failure. Clin Auton Res. 2025 Mar 7 Epub 2025 Mar 07
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  3. Liu T, Johnson M, Badihian N, Harmsen WS, Mandrekar J, Jackson LM, Benarroch EE, Sandroni P, Low PA, Singer W, Coon EA. Clinical and Laboratory Features Predict Phenoconversion from Sporadic Adult-onset Ataxia to Multiple System Atrophy. Cerebellum. 2024 Dec 5; 24 (1):2 Epub 2024 Dec 05
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  4. Krismer F, Fanciulli A, Meissner WG, Coon EA, Wenning GK. Multiple system atrophy: advances in pathophysiology, diagnosis, and treatment. Lancet Neurol. 2024 Dec; 23 (12):1252-1266
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  5. Mustafa R, Braksick SA, Cutsforth-Gregory JK, Burkholder DB, Flanagan EP, Graff-Radford J, Boes CJ, Leep Hunderfund AN, Jones LK, Coon EA. Curriculum Innovations: A Novel Neurology Clinician-Educator Program. Neurol Educ. 2024 Dec; 3 (4):e200175 Epub 2024 Nov 27
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  6. Rashed HR, Staff NP, Milone M, Mauermann ML, Berini S, Cheshire WP, Coon EA, Fealey RD, Sorenson E, Cutsforth-Gregory J, Benarroch EE, Sandroni P, Low PA, Singer W, Shouman K. Autonomic impairment in primary lateral sclerosis. Clin Auton Res. 2024 Aug; 34 (4):421-425 Epub 2024 June 12
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  7. Millar Vernetti P, Norcliffe-Kaufmann L, Palma JA, Biaggioni I, Shibao CA, Peltier A, Freeman R, Gibbons C, Goldstein DS, Low PA, Singer W, Coon EA, Miglis MG, Wenning GK, Fanciulli A, Vernino S, Betensky RA, Kaufmann H. Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study. Brain. 2024 Jul 5; 147 (7):2440-2448
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  8. Ziebart RL, Coon EA, Sartori-Valinotti JC. Role of thermoregulatory sweat test in the diagnosis of facial flushing: A retrospective case series. J Am Acad Dermatol. 2024 Apr; 90 (4):841-842 Epub 2023 Dec 07
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  9. Badihian N, Christy AL, Boes CJ, Gutmann L, Coon EA. The Auxiliary to the American Academy of Neurology. Neurology. 2024 Mar 12; 102 (5):e209142 Epub 2024 Feb 06
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  10. Badihian N, Savica R, Adler CH, Wszolek ZK, Jackson LM, Benarroch EE, Sandroni P, Low PA, Singer W, Coon EA. Clinical Characteristics and Outcomes in Young-Onset Multiple System Atrophy. Mov Disord Clin Pract. 2024 Mar; 11 (3):220-226 Epub 2023 Nov 23
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  11. Mauricio EA, Coon EA, Driver-Dunckley ED, English SW Jr, Cutsforth-Gregory JK, Grill MF, Martinez-Thompson JM, Jones LK, for Mayo Clinic Adult Neurology Residency Program Leadership. Education Research: Virtual Residency Interviews and the Second Look: The Mayo Clinic Neurology Tri-Site Experience. Neurol Educ. 2023 Dec 22; 2 (4):e200095 Epub 2023 Oct 16
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  12. Coon EA, West CP, Jones LK. Can We Improve Burnout in Neurology by Targeting Residency Program Resiliency? Neurol Educ. 2023 Sep 25; 2 (3):e200085 Epub 2023 July 06
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  13. Kerber AA, Coon EA, Reichard KK, Chen D, Pongdee T, Chiarella SE. Systemic mastocytosis presenting with episodic rigors. J Allergy Clin Immunol Pract. 2023 Sep; 11 (9):2955-2956 Epub 2023 June 12
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  14. Schipani BE, Bailey ES, Hooshmand SJ, Badihian N, Sandroni P, Benarroch EE, Bower JH, Low PA, Singer W, Coon EA. Sex and Gender Influence Urinary Symptoms and Management in Multiple System Atrophy. J Mov Disord. 2023 May; 16 (2):196-201 Epub 2023 May 24
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  15. Rael S, Badihian N, Smith KM, Coon EA. Chorea Associated with Lamotrigine Use. Tremor Other Hyperkinet Mov (N Y). 2023; 13:5. Epub 2023 Feb 20.
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  16. McCarter SJ, Coon EA, Benarroch EE, Silber MH, St Louis EK. Nocturnal Pulse Event Frequency Is Reduced in Multiple System Atrophy. Ann Neurol. 2023 Jan; 93 (1):205-212 Epub 2022 Nov 02
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  17. Coon EA, Castillo AM, Lesnick TG, Raghavan S, Mielke MM, Reid RI, Windham BG, Petersen RC, Jack CR, Graff-Radford J, Vemuri P. Blood pressure changes impact corticospinal integrity and downstream gait and balance control. Neurobiol Aging. 2022 Dec; 120:60-67 Epub 2022 Aug 27
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  18. Carlos AF, Sekiya H, Koga S, Pham NTT, Ali F, Botha H, Clark HM, Coon EA, Lowe V, Ahlskog JE, Trejo-Lopez JA, Dickson DW, Whitwell JL, Josephs KA. Tau-PET and multimodal imaging in clinically atypical multiple system atrophy masquerading as progressive supranuclear palsy. Parkinsonism Relat Disord. 2022 Aug; 101:9-14 Epub 2022 June 16
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  19. Coon EA, Golden EP, Bryarly M, McGregor T, Nguyen BN, Moutvic MA, Cutsforth-Gregory JK, Stevens PM, Chou CZ, Rhee L, Vernino S. A call for multiple system atrophy centers of excellence. Clin Auton Res 2022 Jun; 32 (3):205-208 Epub 2022 May 12
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  20. Coon EA, Smith KM, Boes CJ. Dr. Betty Clements: Breaking Gender Barriers in the Air Force and Neurology. Neurology. 2022 May 17; 98 (20):841-846 Epub 2022 Mar 15
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  21. Chou CZ, Ahlskog JE, Klassen BT, Coon EA, Ali F, Bower JH, Savica R, Hassan A. Utility of routine surface electrophysiology to screen for functional tremor prior to surgical treatment of essential tremor. Clin Park Relat Disord. 2022; 7:100149 Epub 2022 June 16
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  22. Badihian N, Jackson LM, Klassen BT, Hassan A, Low PA, Singer W, Coon EA. The Effects of Deep Brain Stimulation in Patients with Multiple System Atrophy. J Parkinsons Dis 2022; 12 (8):2595-2600
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  23. Smith KM, Boes CJ, Coon EA. Women in the Mayo Clinic Department of Neurology in its early years. Proc (Bayl Univ Med Cent). 2022; 35 (5):649-654 Epub 2022 May 31
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  24. Lamotte G, Coon EA, Suarez MD, Sandroni P, Benarroch E, Cutsforth-Gregory JK, Mauermann ML, Berini SE, Shouman K, Sletten D, Goodman BP, Low PA, Singer W. Standardized Autonomic Testing in Patients With Probable Radiation-Induced Afferent Baroreflex Failure. Hypertension. 2022 Jan; 79(1):50-56. Epub 2021 Nov 05.
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  25. Lamotte G, Sandroni P, Cutsforth-Gregory JK, Berini SE, Benarroch EE, Shouman K, Mauermann ML, Anderson J, Low PA, Singer W, Coon EA. Clinical presentation and autonomic profile in Ross syndrome. J Neurol. 2021 Oct; 268 (10):3852-3860 Epub 2021 Apr 03
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  26. Schmeichel AM, Coon EA, Parisi JE, Singer W, Low PA, Benarroch EE. Loss of putative GABAergic neurons in the ventrolateral medulla in multiple system atrophy. Sleep. 2021 Sep 13; 44 (9)
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  27. Lamotte G, Coon EA, Suarez MD, Sandroni P, Benarroch EE, Cutsforth-Gregory JK, Mauermann ML, Berini SE, Shouman K, Sletten D, Goodman BP, Low PA, Singer W. Natural History of Afferent Baroreflex Failure in Adults. Neurology. 2021 Jul 13; 97(2):e136-e144. Epub 2021 May 04.
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  28. Shouman K, Vanichkachorn G, Cheshire WP, Suarez MD, Shelly S, Lamotte GJ, Sandroni P, Benarroch EE, Berini SE, Cutsforth-Gregory JK, Coon EA, Mauermann ML, Low PA, Singer W. Autonomic dysfunction following COVID-19 infection: an early experience. Clin Auton Res. 2021 Jun; 31 (3):385-394 Epub 2021 Apr 16
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  29. Cheshire WP, Freeman R, Gibbons CH, Cortelli P, Wenning GK, Hilz MJ, Spies JM, Lipp A, Sandroni P, Wada N, Mano T, Kim HA, Kimpinski K, Iodice V, Idiaquez J, Thaisetthawatkul P, Coon EA, Low PA, Singer W. Corrigendum to "Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology" [Clin. Neurophysiol. 132(2) (2021) 666-682]. Clin Neurophysiol. 2021 May; 132 (5):1194 Epub 2021 Mar 06
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  30. Coon EA, Ahlskog JE. My Treatment Approach to Multiple System Atrophy. Mayo Clin Proc. 2021 Mar; 96 (3):708-719
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  31. Cheshire WP, Freeman R, Gibbons CH, Cortelli P, Wenning GK, Hilz MJ, Spies JM, Lipp A, Sandroni P, Wada N, Mano A, Ah Kim H, Kimpinski K, Iodice V, Idiaquez J, Thaisetthawatkul P, Coon EA, Low PA, Singer W. Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology. Clin Neurophysiol. 2021 Feb; 132 (2):666-682 Epub 2020 Dec 22
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  32. Jackson L, Klassen BT, Hassan A, Bower JH, Matsumoto JY, Coon EA, Ali F. Utility of tremor electrophysiology studies. Clin Park Relat Disord. 2021; 5:100108 Epub 2021 Sept 24
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  33. Coon EA. Autonomic Dysfunction in the Synucleinopathies. Semin Neurol. 2020 Oct; 40 (5):492-501 Epub 2020 Sept 09
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  34. Boes CJ, Burkholder DB, Coon EA, Cutsforth-Gregory JK, Klaas JP, Jones LK Jr. Reciprocal Development and Progressive Responsibility: The History of the Mayo Clinic Neurology Residency. Mayo Clin Proc Innov Qual Outcomes. 2020 Oct; 4 (5):478-498 Epub 2020 Oct 06
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  35. Coon EA, Mandrekar JN, Berini SE, Benarroch EE, Sandroni P, Low PA, Singer W. Predicting phenoconversion in pure autonomic failure. Neurology. 2020 Aug 18; 95 (7):e889-e897 Epub 2020 June 16
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  36. McCarter SJ, Coon EA, Savica R, St Louis EK, Bower JH, Benarroch EE, Sandroni P, Low P, Singer W. Lower Vitamin B12 Level at Multiple System Atrophy Diagnosis Is Associated With Shorter Survival. Mov Disord. 2020 Aug; 35 (8):1462-1466 Epub 2020 Apr 22
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  37. Coon EA, Cheshire WP Jr. Sweating Disorders. Continuum (Minneap Minn). 2020 Feb; 26 (1):116-137
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  38. Coon EA, Singer W. Synucleinopathies. Continuum (Minneap Minn). 2020 Feb; 26 (1):72-92
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  39. Jackson L, Turcano P, Stitt D, Coon E, Savica R. Autonomic Testing Profiles in Scans without Evidence of Dopaminergic Deficit (SWEDD). J Parkinsons Dis 2020; 10 (3):945-949
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  40. Corfits J, Singer W, Sandroni P, Fealey RD, Coon EA, Benarroch EE, Berini SE, Mauermann ML, Sletten DM, Cutsforth-Gregory JK, Schmelzer JD, Low PA. Elimination of spurious absent sweat response in QSWEAT recordings. Auton Neurosci. 2019 Dec; 222:102589 Epub 2019 Oct 23
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  41. McCarter SJ, Feemster JC, Tabatabai GM, Sandness DJ, Timm PC, McCarter AR, Talley HN, Junna MR, Savica R, Singer W, Coon EA, Benarroch EE, Josephs KA, Boeve BF, Silber MH, St Louis EK. Submentalis Rapid Eye Movement Sleep Muscle Activity: A Potential Biomarker for Synucleinopathy. Ann Neurol. 2019 Dec; 86 (6):969-974
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  42. Coon EA, Singer W, Low PA. Pure Autonomic Failure. Mayo Clin Proc. 2019 Oct; 94 (10):2087-2098 Epub 2019 Sept 09
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  43. Jackson L, Coon EA, Ahlskog JE, Bower JH, Sandroni P, Benarroch EE, Mandrekar JN, Low PA, Singer W. Earlier age of onset in multiple system atrophy with smoking and heavy alcohol use. Parkinsonism Relat Disord. 2019 Sep; 66:212-215 Epub 2019 July 17
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  44. Singer W, Dietz AB, Zeller AD, Gehrking TL, Schmelzer JD, Schmeichel AM, Gehrking JA, Suarez MD, Sletten DM, Minota Pacheco KV, Coon EA, Sandroni P, Benarroch EE, Fealey RD, Matsumoto JY, Bower JH, Hassan A, McKeon A, Windebank AJ, Mandrekar JN, Low PA. Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy. Neurology. 2019 Jul 2; 93 (1):e77-e87 Epub 2019 May 31
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  45. Stankovic I, Quinn N, Vignatelli L, Antonini A, Berg D, Coon E, Cortelli P, Fanciulli A, Ferreira JJ, Freeman R, Halliday G, Hoglinger GU, Iodice V, Kaufmann H, Klockgether T, Kostic V, Krismer F, Lang A, Levin J, Low P, Mathias C, Meissner WG, Kaufmann LN, Palma JA, Panicker JN, Pellecchia MT, Sakakibara R, Schmahmann J, Scholz SW, Singer W, Stamelou M, Tolosa E, Tsuji S, Seppi K, Poewe W, Wenning GK, Movement Disorder Society Multiple System Atrophy Study Group. A critique of the second consensus criteria for multiple system atrophy. Mov Disord. 2019 Jul; 34 (7):975-984 Epub 2019 Apr 29
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  46. Coon EA, Nelson RM, Sletten DM, Suarez MD, Ahlskog JE, Benarroch EE, Sandroni P, Mandrekar JN, Low PA, Singer W. Sex and gender influence symptom manifestation and survival in multiple system atrophy. Auton Neurosci. 2019 Jul; 219:49-52. Epub 2019 Apr 24.
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  47. Minota K, Coon EA, Benarroch EE. Neurologic aspects of sweating and its disorders. Neurology. 2019 May 21; 92 (21):999-1005 Epub 2019 Apr 24
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  48. Cutsforth-Gregory JK, McKeon A, Coon EA, Sletten DM, Suarez M, Sandroni P, Singer W, Benarroch EE, Fealey RD, Low PA. Ganglionic Antibody Level as a Predictor of Severity of Autonomic Failure. Mayo Clin Proc. 2018 Oct; 93(10):1440-1447. Epub 2018 Aug 28.
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  49. Singh TD, Swanson A, Burrows AM, Clarke M, Shah S, Ali F, Coon EA. Teaching NeuroImages: Not a typical spinal mass. Neurology. 2018 Aug 21; 91 (8):e790-e791
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  50. Coon EA, Koehler PJ, Boes CJ. Denise Louis-Bar: The eponymous woman of Louis-Bar syndrome. Neurology. 2018 Jul 24; 91 (4):175-179
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  51. Coon EA, Ahlskog JE, Silber MH, Fealey RD, Benarroch EE, Sandroni P, Mandrekar JN, Low PA, Singer W. Do selective serotonin reuptake inhibitors improve survival in multiple system atrophy? Parkinsonism Relat Disord. 2018 Mar; 48:51-53 Epub 2017 Dec 14
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  52. Coon EA, Cutsforth-Gregory JK, Benarroch EE. Neuropathology of autonomic dysfunction in synucleinopathies. Mov Disord. 2018 Mar; 33 (3):349-358 Epub 2018 Jan 03
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  53. Coon EA, Benarroch EE. DNA damage response: Selected review and neurologic implications. Neurology. 2018 Feb 20; 90 (8):367-376 Epub 2018 Jan 19
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  54. Garcia MD, Pulido JS, Coon EA, Chen JJ. Ocular features of multiple system atrophy. J Clin Neurosci. 2018 Jan; 47:234-239 Epub 2017 Oct 21
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  55. Coon EA, Low PA. Thermoregulation in Parkinson disease. Handb Clin Neurol. 2018; 157:715-725
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  56. Mittal SO, Klassen BT, Hassan A, Bower JH, Coon EA. Acute Worsening of Tics on Varenicline. Clin Neuropharmacol. 2017 Sep/Oct; 40 (5):231-232
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  57. Singer W, Berini SE, Sandroni P, Fealey RD, Coon EA, Suarez MD, Benarroch EE, Low PA. Pure autonomic failure: Predictors of conversion to clinical CNS involvement. Neurology. 2017 Mar 21; 88 (12):1129-1136 Epub 2017 Feb 15
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  58. Coon EA, Fealey RD, Sletten DM, Mandrekar JN, Benarroch EE, Sandroni P, Low PA, Singer W. Anhidrosis in multiple system atrophy involves pre- and postganglionic sudomotor dysfunction. Mov Disord. 2017 Mar; 32(3):397-404. Epub 2016 Nov 10.
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  59. Coon EA, Schmeichel AM, Parisi JE, Cykowski MD, Low PA, Benarroch EE. Medullary neuronal loss is not associated with alpha-synuclein burden in multiple system atrophy. Mov Disord. 2016 Dec; 31 (12):1802-1809 Epub 2016 Sept 15
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  60. Cutsforth-Gregory JK, Fealey RD, Harreld FA, Coon EA. Severe compensatory hyperhidrosis after thoracic sympathectomy. Neurol Clin Pract. 2016 Dec; 6 (6):e49-e50
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  61. Labbé C, Heckman MG, Lorenzo-Betancor O, Murray ME, Ogaki K, Soto-Ortolaza AI, Walton RL, Fujioka S, Koga S, Uitti RJ, van Gerpen JA, Petersen RC, Graff-Radford NR, Younkin SG, Boeve BF, Cheshire WP Jr, Low PA, Sandroni P, Coon EA, Singer W, Wszolek ZK, Dickson DW, Ross OA. MAPT haplotype diversity in multiple system atrophy. Parkinsonism Relat Disord. 2016 Sep; 30:40-5. Epub 2016 Jun 16.
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  62. Coon EA, Fealey RD, Benarroch EE, Sandroni P, Low PA, Singer W. Purple hands in multiple system atrophy: Global anhidrosis with preserved acral sweating. Neurology. 2016 Jun 14; 86 (24):2314
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  63. Coon EA, Ahlskog JE, Patterson MC, Niu Z, Milone M. Expanding Phenotypic Spectrum of NKX2-1-Related Disorders-Mitochondrial and Immunologic Dysfunction. JAMA Neurol. 2016 Feb; 73 (2):237-8
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  64. St Louis EK, Duwell EJ, Orbelo DM, Benarroch EE, Coon EA, Boeve BF, Silber MH. A 76 Year-Old Woman with Sleep and Waking Stridor, Sleep Talking, Orthostatic Hypotension, and Imbalance. J Clin Sleep Med. 2016 Jan; 12 (1):143-5
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  65. Coon EA, Sletten DM, Suarez MD, Mandrekar JN, Ahlskog JE, Bower JH, Matsumoto JY, Silber MH, Benarroch EE, Fealey RD, Sandroni P, Low PA, Singer W. Clinical features and autonomic testing predict survival in multiple system atrophy. Brain. 2015 Dec; 138(Pt 12):3623-31. Epub 2015 Sep 13.
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  66. Cykowski MD, Coon EA, Powell SZ, Jenkins SM, Benarroch EE, Low PA, Schmeichel AM, Parisi JE. Expanding the spectrum of neuronal pathology in multiple system atrophy. Brain. 2015 Aug; 138 (Pt 8):2293-309 Epub 2015 May 16
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  67. Palma JA, Fernandez-Cordon C, Coon EA, Low PA, Miglis MG, Jaradeh S, Bhaumik AK, Dayalu P, Urrestarazu E, Iriarte J, Biaggioni I, Kaufmann H. Prevalence of rem sleep behavior disorder in multiple system atrophy: a multicenter study and meta-analysis. Clin Auton Res. 2015 Feb; 25(1):69-75.
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  68. Coon EA, Kramer NM, Fabris RR, Burkholder DB, Klaas JP, Graff-Radford J, Moore SA, Wijdicks EFM, Britton JW, Jones LK Jr. Structured handoff checklists improve clinical measures in patients discharged from the neurointensive care unit. Neurol Clin Pract. 2015 Feb; 5 (1):42-49
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  69. Coon EA, Hassan A. Did the "Woman in the Attic" in Jane Eyre Have Huntington Disease? Tremor Other Hyperkinet Mov (N Y). 2015; 5:323 Epub 2015 July 21
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  70. Zalewski NL, Coon EA, Cetta F Jr, Taggart NW, Flemming KD. Successful endovascular repair of an unusual right-to-left shunt presenting with cerebral ischemia. J Clin Neurosci. 2014 Jul; 21(7):1257-8. Epub 2013 Dec 13.
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  71. Coon EA, Zalewski NL, Hoffman EM, Tefferi A, Flemming KD. Nilotinib treatment-associated cerebrovascular disease and stroke. Am J Hematol 2013 Jun; 88 (6):534-5 Epub 2013 May 13
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  72. Coon EA, Daube JR, Dejesus-Hernandez M, Adeli A, Savica R, Parisi JE, Dickson DW, Josephs KA, Baker MC, Johnson KA, Ivnik RJ, Petersen RC, Knopman DS, Boylan KB, Rademakers R, Boeve BF. Clinical and electrophysiologic variability in amyotrophic lateral sclerosis within a kindred harboring the C9ORF72 repeat expansion. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Mar; 14 (2):132-7 Epub 2012 Oct 04
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  73. Tada M, Coon EA, Osmand AP, Kirby PA, Martin W, Wieler M, Shiga A, Shirasaki H, Tada M, Makifuchi T, Yamada M, Kakita A, Nishizawa M, Takahashi H, Paulson HL. Coexistence of Huntington's disease and amyotrophic lateral sclerosis: a clinicopathologic study. Acta Neuropathol. 2012 Nov; 124 (5):749-60 Epub 2012 June 27
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  74. Hassan A, Mateen FJ, Coon EA, Ahlskog JE. Painful legs and moving toes syndrome: a 76-patient case series. Arch Neurol. 2012 Aug; 69(8):1032-8.
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  75. Coon EA, Whitwell JL, Jack CR Jr, Josephs KA. Primary lateral sclerosis as progressive supranuclear palsy: diagnosis by diffusion tensor imaging. Mov Disord. 2012 Jun; 27 (7):903-6 Epub 2012 Apr 19
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  76. Coon EA, Patterson MC. Teaching neuroimages: call it as you see it: evolution of bilateral striatal necrosis. Neurology. 2012 May 8; 78(19):e123.
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  77. Coon EA, Laughlin RS. Burning mouth syndrome in Parkinson's disease: dopamine as cure or cause? J Headache Pain. 2012 Apr; 13 (3):255-7 Epub 2012 Feb 10
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  78. Coon EA, Whitwell JL, Parisi JE, Dickson DW, Josephs KA. Right temporal variant frontotemporal dementia with motor neuron disease. J Clin Neurosci. 2012 Jan; 19 (1):85-91 Epub 2011 Nov 02
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  79. Coon EA, Sorenson EJ, Whitwell JL, Knopman DS, Josephs KA. Predicting survival in frontotemporal dementia with motor neuron disease. Neurology. 2011 May 31; 76 (22):1886-93
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  80. Cornell RA, Yemm EA, Bonde G, Li W, d’Alencon C, Wegman L, Eisen J, Zahs A. Touchtone promotes survival of embryonic melanophores in zebrafish. Mech Develop. 2004; 121(11):1365-76.