Casey M. Clements, M.D., Ph.D.

  1. Emergency Medicine Physician
  1. McGuire SS, Finley JL, Gazley BF, Mullan AF, Clements CM. The Team Is Not Okay: Violence in Emergency Departments Across Disciplines in a Health System. West J Emerg Med. 2023 Feb 1; 24 (2):169-177 Epub 2023 Feb 01
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  2. Nelson DM, Madsen BE, Kopecky SL, Jenson CE, Loth AR, Mullan AF, Clements CM, Lin G. Retrospective validation of acute heart failure risk stratification in the emergency department. Heart Lung. 2023 Jan-Feb; 57:31-40 Epub 2022 Aug 22
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  3. McCoy RG, Campbell RL, Mullan AF, Bucks CM, Clements CM, Reichard RR, Jeffery MM. Changes in all-cause and cause-specific mortality during the first year of the COVID-19 pandemic in Minnesota: population-based study. BMC Public Health. 2022 Dec 7; 22 (1):2291 Epub 2022 Dec 07
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  4. Mikula AL, Ransom RC, Nesvick CL, Douse DM, Smith AJ, Maldonado G, Clements CM, Kim BD, Driscoll CL, Elder BD. Toothbrush Oropharyngeal Impalement With Spinal Canal Compromise: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2022 Dec 1; 23 (6):e377-e378 Epub 2022 Sept 26
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  5. McCoy RG, Mullan AF, Jeffery MM, Bucks CM, Clements CM, Campbell RL. Excess All-Cause and Cause-Specific Mortality Among People with Diabetes During the COVID-19 Pandemic in Minnesota: Population-Based Study. J Gen Intern Med. 2022 Sep; 37 (12):3228-3231 Epub 2022 June 29
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  6. Zhang Z, Chen L, Xu P, Wang Q, Zhang J, Chen K, Clements CM, Celi LA, Herasevich V, Hong Y. Effectiveness of automated alerting system compared to usual care for the management of sepsis. NPJ Digit Med. 2022 Jul 19; 5 (1):101 Epub 2022 July 19
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  7. McGuire SS, Mullan AF, Clements CM. Workplace Violence in the Emergency Department: Case Study on Staff and Law Enforcement Disagreement on Reportable Crimes. Int J Environ Res Public Health. 2022 Jun 2; 19 (11) Epub 2022 June 02
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  8. McGuire SS, Gazley B, Majerus AC, Mullan AF, Clements CM. Impact of the COVID-19 pandemic on workplace violence at an academic emergency department. Am J Emerg Med. 2022 Mar; 53:285.e1-285.e5 Epub 2021 Sept 23
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  9. Clements CM, Hanson KT, Zavaleta KW, Stitz AM, Clark SE, Schwarz RR, Homan JR, Larson MV, Habermann EB, Gazelka HM, Mayo Clinic Care Network Acute Opioid Prescribing Collaborative. Collaborative improvement on acute opioid prescribing among diverse health systems. PLoS One. 2022; 17 (6):e0270179 Epub 2022 June 23
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  10. Lipatov K, Daniels CE, Park JG, Elmer J, Hanson AC, Madsen BE, Clements CM, Gajic O, Pickering BW, Herasevich V. Implementation and evaluation of sepsis surveillance and decision support in medical ICU and emergency department. Am J Emerg Med. 2022 Jan; 51:378-383 Epub 2021 Nov 11
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  11. Tehranian S, Shawwa K, Barreto EF, Clements CM, Kashani K. Impact of chloride-rich crystalloids on sepsis-associated community-acquired acute kidney injury recovery in critically ill patients. J Nephrol. 2022 Jan; 35 (1):285-292 Epub 2021 May 20
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  12. Sharain K, Vasile VC, Sandoval Y, Donato LJ, Clements CM, Newman JS, Karon BS, Jaffe AS. The Elevated High-Sensitivity Cardiac Troponin T Pilot: Diagnoses and Outcomes. Mayo Clin Proc. 2021 Sep; 96 (9):2366-2375 Epub 2021 May 13
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  13. Nestler DM, Laack TA, Scanlan-Hanson L, Clements CM, Sadosty AT, Walker LE. A Comprehensive Departmental Care Review Model: Requirements, Structure, and Flow. Jt Comm J Qual Patient Saf. 2021 Aug; 47 (8):503-509 Epub 2021 May 21
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  14. McGuire SS, Mullan AF, Clements CM. Unheard Victims: Multidisciplinary Incidence and Reporting of Violence in an Emergency Department. West J Emerg Med. 2021 May 07; 22(3):702-709.
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  15. Zavaleta KW, Philpot LM, Cunningham JL, Gazelka HM, Geyer HL, Rismeyer DL, Stitz AM, Clements CM. Why we still prescribe so many opioids: A qualitative study on -barriers and facilitators to prescribing guideline implementation. J Opioid Manag. 2021 Mar-Apr; 17 (2):115-124
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  16. O'Horo JC, Cerhan JR, Cahn EJ, Bauer PR, Temesgen Z, Ebbert J, Abril A, Abu Saleh OM, Assi M, Berbari EF, Bierle DM, Bosch W, Burger CD, Cano Cevallos EJ, Clements CM, Carmona Porquera EM, Castillo Almeida NE, Challener DW, Chesdachai S, Comba IY, Corsini Campioli CG, Crane SJ, Dababneh AS, Enzler MJ, Fadel HJ, Ganesh R, De Moraes AG, Go JR, Gordon JE, Gurram PR, Guru PK, Halverson EL, Harrison MF, Heaton HA, Hurt R, Kasten MJ, Lee AS, Levy ER, Libertin CR, Mallea JM, Marshall WF 3rd, Matcha G, Meehan AM, Franco PM, Morice WG 2nd, O'Brien JJ, Oeckler R, Ommen S, Oravec CP, Orenstein R, Ough NJ, Palraj R, Patel BM, Pureza VS, Pickering B, Phelan DM, Razonable RR, Rizza S, Sampathkumar P, Sanghavi DK, Sen A, Siegel JL, Singbartl K, Shah AS, Shweta F, Speicher LL, Suh G, Tabaja H Jr, Tande A, Ting HH, Tontz RC 3rd, Vaillant JJ, Vergidis P, Warsame MY, Yetmar ZA, Zomok CCD, Williams AW, Badley AD. Outcomes of COVID-19 With the Mayo Clinic Model of Care and Research. Mayo Clin Proc. 2021 Mar; 96 (3):601-618 Epub 2020 Dec 26
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  17. Sevransky JE, Rothman RE, Hager DN, Bernard GR, Brown SM, Buchman TG, Busse LW, Coopersmith CM, DeWilde C, Ely EW, Eyzaguirre LM, Fowler AA, Gaieski DF, Gong MN, Hall A, Hinson JS, Hooper MH, Kelen GD, Khan A, Levine MA, Lewis RJ, Lindsell CJ, Marlin JS, McGlothlin A, Moore BL, Nugent KL, Nwosu S, Polito CC, Rice TW, Ricketts EP, Rudolph CC, Sanfilippo F, Viele K, Martin GS, Wright DW, VICTAS Investigators, Clements CM, Gajic O, Kashyap R. Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial. JAMA. 2021 Feb 23; 325 (8):742-750
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  18. Kooda KJ, Rudis M, Mara K, Clements C, Bellolio F. Critically Ill Health Care-Associated Urinary Tract Infection: Broad vs. Narrow Antibiotics in the Emergency Department Have Similar Outcomes. J Emerg Med. 2021 Jan; 60 (1):8-16 Epub 2020 Oct 07
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  19. Heaton HA, Luke A, Sztajnkrycer MD, Clements CM, De Moraes AG, Raukar NP. Best Practices in Managing Cardiac Arrest in the Emergency Department During the COVID-19 Pandemic. Mayo Clin Proc. 2020 Dec; 95 (12):2704-2708 Epub 2020 Oct 16
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  20. Clements CM, Oeckler RA, Heaton HA, Diedrich DA, Brown DR, Sampathkumar P. Creating Successful Emergency Department and Intensive Care Unit Team Dynamics. Mayo Clin Proc. 2020 Sep; 95 (9S):S35-S37 Epub 2020 July 30
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  21. Gazelka HM, Clements CM, Cunningham JL, Geyer HL, Lovely JK, Olson CL, Philpot LM, Porter SB, Witt TJ, Zavaleta KW, Habermann EB. An Institutional Approach to Managing the Opioid Crisis. Mayo Clin Proc. 2020 May; 95 (5):968-981 Epub 2020 Mar 11
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  22. Tootooni MS, Pasupathy KS, Heaton HA, Clements CM, Sir MY. CCMapper: An adaptive NLP-based free-text chief complaint mapping algorithm. Comput Biol Med. 2019 Oct; 113:103398 Epub 2019 Aug 21
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  23. Zavaleta KW, Clements CM. Addressing Safe Opioid Prescribing: A Structured Framework for Organizational Needs Assessment. Mayo Clin Proc Innov Qual Outcomes. 2019 Jun; 3 (2):246-247 Epub 2019 May 27
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  24. Larson LA, Finley JL, Gross TL, McKay AK, Moenck JM, Severson MA, Clements CM. Using a Potentially Aggressive/Violent Patient Huddle to Improve Health Care Safety. Jt Comm J Qual Patient Saf. 2019 Feb; 45 (2):74-80 Epub 2019 Jan 10
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  25. Ebbert JO, Philpot LM, Clements CM, Lovely JK, Nicholson WT, Jenkins SM, Lamer TJ, Gazelka HM. Attitudes, Beliefs, Practices, and Concerns Among Clinicians Prescribing Opioids in a Large Academic Institution. Pain Med. 2018 Sep 1; 19 (9):1790-1798
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  26. Walker LE, Nestler DM, Laack TA, Clements CM, Erwin PJ, Scanlan-Hanson L, Bellolio MF. Clinical care review systems in healthcare: a systematic review. Int J Emerg Med. 2018 Feb 8; 11 (1):6 Epub 2018 Feb 08
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  27. Heaton HA, Nestler DM, Sadosty AT, Ernste VK, Boggust A, Clements CM, Marisamy G, Koenig KR, Pasupathy KS, Hellmich TR. R-EME: RTLS-event mapping engine applications in emergency medicine. Am J Emerg Med 2018 Feb; 36 (2):324-325 Epub 2017 July 16
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  28. Hellmich TR, Clements CM, El-Sherif N, Pasupathy KS, Nestler DM, Boggust A, Ernste VK, Marisamy G, Koenig KR, Hallbeck MS. Contact tracing with a real-time location system: A case study of increasing relative effectiveness in an emergency department. Am J Infect Control. 2017 Dec 01; 45(12):1308-1311. Epub 2017 Sep 28.
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  29. Karon BS, Tolan NV, Wockenfus AM, Block DR, Baumann NA, Bryant SC, Clements CM. Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients. Clin Biochem. 2017 Nov; 50 (16-17):956-958 Epub 2017 May 25
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  30. Jentzer JC, Clements CM, Murphy JG, Wright RS, Scott Wright R. Recent developments in the management of patients resuscitated from cardiac arrest. J Crit Care. 2017 Jun; 39:97-107 Epub 2017 Feb 16
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  31. Jentzer JC, Clements CM, Wright RS, White RD, Jaffe AS. Improving Survival From Cardiac Arrest: A Review of Contemporary Practice and Challenges. Ann Emerg Med. 2016 Dec; 68 (6):678-689 Epub 2016 June 16
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  32. Blevins CH, Clements CM. Images in emergency medicine. A 60-year old man with scleral nodules. Sweet's syndrome. Ann Emerg Med. 2014 Apr; 63(4):495, 501.
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  33. McNally RS, Davis BK, Clements CM, Accavitti-Loper MA, Mak TW, Ting JP. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB. J Biol Chem. 2011 Feb 11; 286(6):4098-106. Epub 2010 Nov 19.
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  34. Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15091-6. Epub 2006 Oct 02.
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  35. MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP. Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha. Cancer Res. 2003 Oct 15; 63(20):6928-34.
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  36. Taxman DJ, MacKeigan JP, Clements C, Bergstralh DT, Ting JP. Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor. Cancer Res. 2003 Aug 15; 63(16):5095-104.
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  37. van Deventer HW, Serody JS, McKinnon KP, Clements C, Brickey WJ, Ting JP. Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. J Immunol. 2002 Aug 1; 169(3):1634-9.
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