Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding
  3. blistering
  4. bloody stools
  5. bone pain
  6. burning
  7. coldness
  8. difficulty in moving
  9. discomfort or pain in chest
  10. enlarged heart
  11. feeling of pressure
  12. fever
  13. hives
  14. infection
  15. inflammation
  16. joint pain
  17. lumps
  18. numbness
  19. paleness of skin
  20. rash
  21. redness
  22. scaring
  23. seizures
  24. shortness of breath, troubled breathing, tightness in chest, or wheezing
  25. soreness
  26. stinging
  27. sweating increased
  28. swelling
  29. swollen joints
  30. tenderness
  31. tingling
  32. ulceration
  33. unusual tiredness or weakness
  34. vomiting of blood or material that looks like coffee grounds
  35. warmness at site
  36. weight gain (occurring together with any of the other symptoms listed before)

Less common

  1. Blue lips and fingernails
  2. convulsions (seizures)
  3. difficulty in speaking, slow speech, or inability to speak
  4. faintness
  5. feeling of heaviness in chest
  6. headache (severe)
  7. inability to move arms, legs, or muscles of the face
  8. nausea and vomiting (occurring together with a headache)
  9. no blood pressure or pulse
  10. pain in back or left arm
  11. painful, red lumps under the skin, mostly on the legs
  12. prominent superficial veins over affected area
  13. stopping of heart
  14. unconsciousness
  15. vision problems (occurring together with a headache)
  16. warmth

Check with your doctor as soon as possible if any of the following side effects occur:

More common

  1. Any change in vision (not occurring with a headache)
  2. coughing, sneezing, sore throat, and stuffy or runny nose
  3. cracked lips
  4. crusting, redness, pain, or sores in mouth or nose
  5. decreased urination
  6. earache or feeling of fullness in the ear
  7. increase or decrease in blood pressure
  8. irregular heartbeat
  9. mental depression
  10. pain in stomach, side, abdomen or back
  11. pain and swelling in leg or foot
  12. skin rash
  13. swelling of abdomen (stomach area)
  14. swelling of face, fingers, hands, feet, or lower legs

Less common

  1. Bone swelling
  2. cramping or pain in stomach (severe)
  3. difficult or painful urination
  4. drowsiness (very severe and continuing)
  5. hallucinations (seeing, hearing, or feeling things that are not there)
  6. hearing loss
  7. heartburn, indigestion, or nausea (severe and continuing)
  8. mood, mental, or personality changes
  9. pain in lower back or side
  10. swollen area that feels sore and tender
  11. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Acid or sour stomach
  2. agitation
  3. anxiety
  4. belching
  5. blurred vision
  6. bloating
  7. burning, crawling, or tingling feeling in the skin
  8. chills
  9. confusion
  10. constipation
  11. darkened urine
  12. diarrhea
  13. dizziness
  14. dryness of skin, mouth, or nose
  15. fast heartbeat
  16. flushing
  17. general feeling of discomfort or illness
  18. hair loss
  19. headache (mild and not occurring together with other side effects)
  20. indigestion
  21. irritability
  22. itching of skin
  23. loss of appetite
  24. mood or mental changes
  25. muscle pain
  26. nausea and vomiting (not occurring together with a headache)
  27. shivering
  28. trouble sleeping
  29. weakness
  30. weight loss

Less common

  1. Anxiety and restlessness (occurring together)
  2. clumsiness or unsteadiness when walking
  3. difficulty sleeping
  4. disorientation
  5. forgetfulness
  6. frequent urination
  7. lethargy
  8. lightheadedness
  9. low body temperature
  10. redness, soreness or itching skin
  11. sores, welting or blisters
  12. sores on genitals
  13. swelling of feet or lower legs
  14. thirst
  15. trembling, sometimes with a flapping movement
  16. weak or feeble pulse
  17. weakness in legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: March 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.