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Rochester, Minn.
The purpose of this study is to establish the clearance rate of sPD-L1 in patients undergoing plasma exchange, and to establish the kinetics of sPD-L1 regeneration in vivo.
The purpose of this study is to collect, isolate and culture progenitor cells. To determine optimal methods for isolation, culture, transfection, and differentiation of these cells with potential therapeutic uses. To act as a central resource for the investigation of these cells for researchers at the Mayo Clinic.
The primary purpose of this study is to determine the serum and urine gadolinium reference ranges in patients with normal renal function being administered Gadobutrol for an enhanced MRI exam.
The primary purpose of this study is to generate pediatric-specific reference ranges that take into account patient sex, age, corrected gestational age, ethnicity, etc., and laboratory variables for various coagulation studies.
The purpose of this study is to collect patient and family DNA and disease data to learn more about how changes in certain genes may be linked to cancer. Some people with cancer may have aquired their disease because they inherited an abnormal (mutated) gene. The researchers of this study want to better understand the risks that are linked to genetic changes in these less well-studied genes. By understanding these risks, it is believed that doctors will be able to give better advice to families with mutations in these genes.
The goal of this study is to collect adipose tissue from healthy and disease patients to understand the biology and potential therapeutic use of mesenchymal stem cells. Adipose collection occurs under local anesthesia with an abdominal biopsy that collects about two grams of fat. The fat is used to isolate and grow mesenchymal stem cells. These function of these cells will be tested for their therapeutic potential.
The purpose of this study is to determine the sensitivity, specificity, positive and negative predictive values of molecular detection of microorganisms, detection of microbial proteins and antibodies against microorganisms, and inflammatory markers (e.g., leukocyte esterase, CRP) in synovial fluid for the diagnosis of prosthetic joint infection (PJI).
This research study is being done to help characterize cardiovascular disease and improve diagnostic tests.
OBJECTIVES
To understand the pathogenesis, molecular mechanisms, and disease progression of heritable cardiovascular disease
To evaluate the incidence of occult heritable cardiovascular disease in various populations.
To correlate imaging and pathological phenotype with genotype to the ends described above.
The purpose of this study is to help identify the biology of heart tumors and understand how and why they form.
The purpose of this study is to obtain excess non-malignant submandibular salivary tissues and clinical data from patients undergoing head & neck surgery, and conduct research activities at Mayo Clinic.
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