Waldenstrom Macroglobulinemia

Overview

Waldenstrom macroglobulinemia (mak-ro-glob-u-lih-NEE-me-uh), also called WM or lymphoplasmacytic lymphoma, is a type of non-Hodgkin's lymphoma. WM is a rare, slow-growing cancer that begins in the immune system. Abnormal white blood cells (lymphocytes) in the bone marrow make an abnormal protein called monoclonal immunoglobulin M (IgM) that thickens the blood plasma. This causes the symptoms of WM.

The most common signs and symptoms include nosebleeds, dizziness, gum bleeding, weight loss, bruising, headache, and numbness or tingling in your hands or feet. Your doctor may also find enlarged lymph glands in your neck, groin or under your arms.

Why choose Mayo Clinic for Waldenstrom macroglobulinemia

• Expertise and experience. Mayo Clinic doctors from multiple specialties have extensive experience in treating Waldenstrom macroglobulinemia and offer coordinated services.
• Active research. Mayo Clinic researchers are actively involved in multiple areas of research and clinical trials to understand and develop treatments for Waldenstrom macroglobulinemia.
• Comprehensive cancer center. Mayo Clinic Cancer Center meets strict standards for a National Cancer Institute comprehensive cancer center, recognizing scientific excellence and a multidisciplinary approach focused on cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minn., and in Jacksonville, Fla., are ranked among the Best Hospitals for cancer by U.S. News & World Report.

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