High blood protein (hyperproteinemia) is an excessively high level of proteins in the bloodstream. Normally, your blood contains relatively small amounts of many types of proteins. A sample of blood drawn from your vein can be tested to measure the amounts of these various proteins in your blood.

See your doctor if you experience:

  • Nausea or poor appetite
  • Diarrhea
  • Unexplained weight loss
  • Severe fatigue
  • Persistent fever
  • Tingling or numbness in your fingers and toes
  • Dizziness or a drop in blood pressure upon standing or sitting

If your doctor suspects that you have a condition that causes high blood protein, he or she may recommend additional blood tests. A total protein test can determine whether you have high blood protein and where it's coming from, for instance, the liver or the bone marrow. A serum protein electrophoresis (SPEP) test separates and measures individual blood proteins, indicating which specific protein type is causing your high blood protein levels. The SPEP is often done when a bone marrow disease is suspected.

Nov. 16, 2011