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Progressive Supranuclear Palsy

Overview

Mayo Clinic neurological specialists evaluate more than 600 patients each year for progressive supranuclear palsy (one of several Parkinson's plus syndromes) through Mayo movement disorders programs. Patients receive state-of-the-art treatment and have opportunities to participate in valuable research studies and clinical trials. Mayo Clinic staff have been at the forefront of Parkinson's disease and Parkinson's plus syndrome research.

Diagnosis

Symptoms vary among patients and can easily be misdiagnosed as Parkinson's disease, Alzheimer's disease or other neurodegenerative disorders. Read more about progressive supranuclear palsy diagnosis.

Treatment Options

Progressive supranuclear palsy has no known cure, though some medications may temporarily control some slowness and balance problems. Read more about progressive supranuclear palsy treatment options.

About Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP) is a rare, adult-onset brain disorder that causes gradual deterioration of groups of brain cells at the base of the brain. This deterioration results in problems controlling gait and balance and in an inability to aim the eyes properly, causing blurring. These symptoms are hallmarks of the disease. "Supranuclear" refers to the nerve endings in the brain above the nuclei concerned with eye movement. "Palsy" means weakness.

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