News May 09, 2024 Expanding the donor pool with acute kidney injury kidneys A study by Mayo Clinic transplant surgeons showed excellent outcomes for patients who received AKI kidneys from donors on temporary dialysis at the time of their donations. March 26, 2024 Using normothermic machine perfusion in combined cardiac and liver transplantation procedures saves more lives Mayo Clinic transplant surgeons describe how successfully using machine perfusion technology in heart and liver transplantation procedures saves lives in a case series published in Transplantation Direct. March 14, 2024 Researchers find promise in new potential treatment for liver failure ROCHESTER, Minn. — A new drug has been shown to increase healing and regeneration of the liver after major surgery, according to a study published in the scientific journal Cell. Researchers hope that this could lead to mo[...] March 06, 2024 Transforming Transplant Initiative aspires to save lives through bioengineering Mayo Clinic is taking steps to bolster the medical marvel of transplantation while addressing the confounding problem of a critical shortage of donor organs. It created the Transforming Transplant Initiative with a bold go[...] Feb. 16, 2024 TKA and THA for patients with previous solid organ transplant Demand has grown for TKA and THA in patients who've had a solid organ transplant (SOT). Mayo Clinic is performing these surgeries for this higher risk population. Dec. 22, 2023 Heart pump improves long-term survival rates of patients with advanced heart disease Studies show the Impella 5.5 heart pump helps improve outcomes for patients with advanced heart disease and impaired kidney function. Nov. 30, 2023 Mayo Clinic surgeons perform first robot-assisted kidney transplant Mayo Clinic in Minnesota performed its first robot-assisted kidney transplant. This is the first such transplant in the state of Minnesota. Read more about this type of surgery and suitable patients to refer. Oct. 28, 2023 Mayo Clinic Transplant Center makes referrals for heart transplant easy The Mayo Clinic Heart Transplant Program medical director explains how Mayo Clinic does everything possible to make the referral process easy, communicate well, share the patient's care and provide high-quality heart tr[...] Oct. 27, 2023 Engineering stem cells to treat liver disease Redirecting human embryonic stem cells to become liver cells with the potential for cell, tissue and organ repair can be a viable alternative to a liver transplant. Oct. 04, 2023 Pediatric metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD) Although MASLD is the primary cause of pediatric liver disease, not all children with MASLD have obesity, which makes it critical to diagnose and treat the root cause. Sept. 27, 2023 Respiratory complications of hematopoietic stem cell transplantation Hematopoietic stem cell transplantation (HCT) is a potentially curative and lifesaving treatment option for hematologic cancers such as leukemia, lymphoma and myeloma. While other aspects of post-HCT care have improved,[...] Aug. 15, 2023 Bypassing the ICU after liver transplant Many patients safely go to the surgical ward after liver transplantation at Mayo Clinic's campus in Florida. Aug. 15, 2023 Advanced heart failure complexities and when to refer for specialty care Daniel S. Yip, M.D., a Mayo Clinic transplant cardiologist, responds to questions about pinpointing heart failure status and when to consider referral for advanced heart failure care. Aug. 10, 2023 Triple transplant: A unique opportunity to transform patients' lives A triple transplant of three solid organs from the same donor concurrently can not only reduce mortality but also help patients return to a pre-disease quality of life. July 20, 2023 Confronting polycystic kidney disease, a silent killer Vicente Torres, M.D., Ph.D., launched a collaboration and a series of laboratory experiments and clinical trials, showing that targeting a molecule called vasopressin could effectively halt cyclic AMP production and slo[...] May 26, 2023 Five ways artificial intelligence promises to transform organ transplant Mayo Clinic transplant specialists talk about the ways they believe artificial intelligence will make a difference for transplantation in the future. April 29, 2023 Mayo Clinic Children's Center specialists perform center's first pediatric transplant with heart-in-a-box technology Mayo Clinic Children's Center specialists perform the center's first pediatric transplant with heart-in-a-box technology. March 10, 2023 6 signs your patient is ready for liver transplant referral A liver transplant surgeon at Mayo Clinic shares six key signs that indicate when it is time to send a patient to a transplant center for evaluation. Feb. 11, 2023 Endoscopic retrograde cholangiography versus percutaneous transhepatic biliary drainage in liver transplant recipients with a Roux-en-Y biliary-enteric anastomosis Study data suggest that endoscopic retrograde cholangiography (ERC) and percutaneous transhepatic biliary drainage (PTBD) have comparable effectiveness in this patient population. Jan. 28, 2023 Top 5 criteria that indicate it's time to refer for kidney transplant A transplant surgeon at Mayo Clinic outlines suggested criteria for referring a patient for a potential kidney transplant. Dec. 17, 2022 Lung transplant program at Mayo Clinic Under the joint leadership of Cassie C. Kennedy, M.D., and Mauricio A. Villavicencio Theoduloz, M.D., the Mayo Clinic Lung Transplant Program focuses on improving referral to waitlist decision efficiency and maintaining[...] Dec. 16, 2022 First-in-state transplant using "heart-in-a-box" perfusion system performed at Mayo Clinic in Arizona Specialists at the Mayo Clinic campus in Arizona performed the first heart transplant in the state using a new perfusion system that improves sustenance of donor hearts, allowing more patients to receive heart transplan[...] Nov. 17, 2022 Mayo Clinic experts hope new race-neutral kidney transplant listing criteria improve access for Black individuals Specialists at Mayo Clinic Transplant Center hope the UNOS 2022 requirement of race-neutral kidney transplant listing criteria eliminates barriers, especially for Black people. Aug. 25, 2022 Amyloidosis, the heart transplant precursor to keep on your diagnostic radar Amyloidosis is not only complex to diagnose but until recently, it was considered fatal. A Mayo Clinic transplant cardiologist explains Mayo Clinic's approach to this disease, including transplant for advanced disease. July 29, 2022 Geographical allocation changes boost heart and lung transplant program at Mayo Clinic in Minnesota An expanded geographical reach with the 2017 to 2018 U.S. heart and lung transplant allocation changes has prompted significant program expansion at Mayo Clinic's Minnesota campus. June 24, 2022 "Liver in a box" offers potential for providing liver transplant to more patients Mayo Clinic in Arizona liver transplant organ preservation options now include an NMP device, which keeps organs alive, oxygenated and metabolically functional in an ex vivo setting. May 25, 2022 Transplant professionals strive to correct MELD score gender disparities National transplant community leadership are proposing Model for End-Stage Liver Disease (MELD) 3.0 to rectify gender disparities in deceased liver transplant. May 25, 2022 Major complications minimal and resolve fully in living kidney donors, yet monitoring is essential A Mayo Clinic study indicates only 2.5% of individuals who had hand-assisted laparoscopic living donor nephrectomy (HALLDN) experienced major complications, and all recovered entirely. March 31, 2022 New protocols expand donor pool for highly sensitized pediatric patients receiving heart transplants Use of induction immunosuppression and removal of antibodies that could affect donor hearts allow use of hearts that historically may have been contraindicated. Feb. 12, 2022 How to optimize referral timing for severe liver disease Timing referral of these patients to discuss transplant or other options is challenging. Disease status can turn quickly, and it's important to not refer too early or late. Jan. 07, 2022 Multidisciplinary sickle cell program includes curative bone marrow transplant A pediatric hematologist/oncologist and trained bone marrow transplant physician at Mayo Clinic in Rochester, Minnesota, describes the program's collaborative approach and her unique role in pediatric sickle cell care. Dec. 28, 2021 Right-fit care for patients with severe lung disease: From clinical trials to transplant A lung transplant surgeon discusses Mayo Clinic's collaboration with local physicians to determine the best treatment for each patient, including transplant, clinical trials or other therapies, or transplant prehabilita[...] Nov. 20, 2021 Liver transplantation for colorectal liver metastases at Mayo Clinic in Jacksonville, Florida Mayo Clinic in Jacksonville, Florida, is one of only a few centers in the U.S. offering liver transplant as a treatment option for highly selected patients with colorectal liver metastases. Nov. 20, 2021 A collaborative approach using liver transplant for perihilar cholangiocarcinoma treatment Julie K. Heimbach, M.D., a transplant surgeon at Mayo Clinic in Rochester, Minnesota, discusses neoadjuvant chemotherapy and liver transplantation in the treatment of perihilar cholangiocarcinoma. Nov. 12, 2021 Mayo Clinic's campus in Rochester, Minnesota, offers new liver transplant programs Mayo Clinic's campus in Rochester, Minnesota, started two programs — a nondirected liver program and paired exchange — to facilitate more liver transplants, especially for patients with concerning symptoms b[...] Aug. 27, 2021 Mayo Clinic in Florida: First hospital in the world to use a new heart pump as bridge to transplant Mayo Clinic in Florida is the only hospital internationally using the new Impella 5.5 heart pump as a bridge to transplant. The pump offers numerous advantages over the left ventricular assist device. Aug. 17, 2021 Order is everything: New procedure for heart-liver transplant averts rejection risk A Mayo Clinic study published in Journal of the American College of Cardiology shows transplanting the liver first in a heart-liver transplant significantly decreases rejection rates for highly sensitized patients. Aug. 17, 2021 Use of weight-loss pharmacotherapy in patients with cirrhosis and in liver transplant recipients More data is needed to establish the safety and efficacy of these agents in the pretransplant and post-transplant settings. Aug. 11, 2021 Organ perfusion systems a boon to heart and lung transplants Transplant specialists at Mayo Clinic in Florida use organ perfusion systems for some heart and lung transplants, resulting in multiple advantages for recipients — including saving lives. June 02, 2021 Individuals with controlled hypertension can safely donate a kidney Many individuals who would've been excluded previously from kidney donation may do so if their hypertension is controlled. A Mayo Clinic study has found it safe long-term for donors. May 18, 2021 New therapies offer improved quality of life for patients who need laryngectomy Surgical options for those who need laryngectomy to date have not satisfied all patients. An otolaryngologist at Mayo Clinic in Arizona talks about his work on alternatives: larynx transplant and 3D-printed prosthetic l[...] May 08, 2021 When it's time to consider organ, tissue or eye donation in trauma care A Mayo Clinic Office of Decedent Affairs specialist and LifeSource coordinator answers questions trauma centers may have about organ, tissue or eye donations from their transferred trauma patients. March 26, 2021 Hepatitis C livers now usable for transplant into patients uninfected with hepatitis C A transplant hepatologist explains findings from a study showing positive outcomes with liver transplant from hepatitis C virus (HCV)-seropositive donors to HCV-seronegative recipients. Feb. 05, 2021 Mayo Clinic offers kidney transplant to patients with high BMI who were previously considered ineligible Amid increasing obesity in the U.S., Mayo Clinic has raised its maximum body mass index (BMI) for kidney transplant, using bariatric surgery pretransplant to widen availability. Jan. 20, 2021 Kidney transplant: Perspectives on optimal referral timing and its challenges A Mayo Clinic transplant surgeon talks about the best time to refer a patient for potential kidney transplant and addresses obstacles to making this happen. Jan. 19, 2021 Mayo Clinic's Pediatric Liver Clinic provides exceptional care for patients requiring transplant Mayo Clinic Pediatric Liver Clinic specialists deliver an extensive evaluation to provide a comprehensive assessment and treatment plan for pediatric patients with liver disease. Dec. 16, 2020 Mayo Clinic in Arizona provides transplants for patients with lower MELD scores rapidly, with encouraging outcomes A unique multidisciplinary approach allows donor pool expansion to include extended criteria donation, ensuring organ allocation to the most suitable patients based on multiple variables. Oct. 09, 2020 Consensus reached on initial treatment of acute graft-versus-host disease in patients who receive bone marrow transplant; nothing definitive yet for secondary treatment There are now two approved second line therapies for treatment of steroid-refractory GVHD ― one for acute GVHD and one for chronic GVHD. Oct. 03, 2020 MitraClip treatment of mitral regurgitation after cardiac transplant: Case report A 72-year-old male who underwent orthotopic cardiac transplantation received MitraClip placement for severe mitral regurgitation, with almost complete resolution of symptoms within weeks of implantation. April 17, 2020 Transplant endocrinology at Mayo Clinic Mayo Clinic Transplant Center's multidisciplinary providers see recipients of solid organ and bone marrow transplants both pre- and post-transplant to address the unique management challenges of each from an endocrine p[...] Nov. 05, 2019 Increasing the number of transplantable lungs Ex vivo lung perfusion can make marginal organs suitable for transplantation. Sept. 14, 2019 Preventing glomerulonephritis after kidney transplant Mayo Clinic's protocol involves close patient surveillance and early treatment of even clinically mild glomerulonephritis. Sept. 18, 2018 Liver transplant for PSC-associated cholangiocarcinoma Mayo Clinic is a pioneer of liver transplantation for cholangiocarcinoma in the setting of primary sclerosing cholangitis (PSC). The treatment involves adjuvant therapy before liver transplantation. June 12, 2018 Partnering with providers for heart transplant care Mayo Clinic is committed to collaborating with providers in the ongoing care of their patients. April 28, 2018 A tool for choosing the optimal organ transplant center A critical resource — the Scientific Registry of Transplant Recipients — helps physicians refer patients for possible organ transplantation. April 14, 2018 Genomic testing: An individualized approach to prevent kidney rejection A Mayo Clinic trial uses blood tests to guide immunosuppression therapies after kidney transplant. March 27, 2018 Bioartificial liver: Potential to avoid transplant Mayo Clinic is developing a bioartificial liver to support patients with acute liver failure. The Mayo Spheroid Reservoir Bioartificial Liver has been shown to reduce the severity of liver disease and improve survival i[...] Medical Professionals Transplant Medicine News