News April 20, 2024 Artificial intelligence shows that social isolation impacts cardiovascular age and mortality rate A new study published in JACC: Advances used artificial intelligence to show how social isolation is linked to cardiac aging and a higher mortality rate. March 26, 2024 Anticoagulation early after bioprosthetic sAVR lowers mortality risk A study in Mayo Clinic Proceedings found that receiving anticoagulation with warfarin early reduced all-cause mortality and thromboembolic events after bioprosthetic sAVR. March 26, 2024 Using normothermic machine perfusion in combined cardiac and liver transplantation procedures saves more lives Mayo Clinic transplant surgeons describe how successfully using machine perfusion technology in heart and liver transplantation procedures saves lives in a case series published in Transplantation Direct. Feb. 20, 2024 Specialist care reduces heart failure-related deaths in adults with congenital heart disease A study published in the Journal of the American Heart Association that compared the outcomes of heart failure (HF) versus non-HF hospitalizations in adults with congenital heart disease found that patients in cardiolog[...] Jan. 17, 2024 Asymptomatic severe aortic stenosis outcomes impacted by atrial fibrillation A recent study shows that atrial fibrillation is a marker of increased risk in patients with asymptomatic aortic stenosis and preserved left ventricular ejection fraction. Dec. 22, 2023 Heart pump improves long-term survival rates of patients with advanced heart disease Studies show the Impella 5.5 heart pump helps improve outcomes for patients with advanced heart disease and impaired kidney function. Nov. 01, 2023 Reducing readmissions using catheter ablation in young patients with atrial fibrillation Study led by Andrew S. Tseng, M.D., reveals that young patients with AFib who undergo catheter ablation are at a lower risk of being readmitted to the hospital. Oct. 28, 2023 Mayo Clinic Transplant Center makes referrals for heart transplant easy The Mayo Clinic Heart Transplant Program medical director explains how Mayo Clinic does everything possible to make the referral process easy, communicate well, share the patient's care and provide high-quality heart tr[...] Sept. 27, 2023 Coronary reactivity assessment associated with lower healthcare costs in patients with angina and nonobstructive coronary artery disease CRT achieves diagnostic certainty in ANOCA; however, the financial effect of CRT on patients hadn't been studied. This Mayo Clinic study assessed how CRT affects healthcare costs in patients with ANOCA. Sept. 27, 2023 Impact of atrial fibrillation on outcomes in very severe aortic valve stenosis The prevalence and impact of AF versus SR on outcomes in vsAS of the native valve is unknown. A Mayo Clinic study examined prognostic significance of AF in vsAS. Sept. 27, 2023 Anticoagulation after bioprosthetic aortic valve replacement: Are the guidelines being followed? Guideline-directed medication adherence is an important quality measure after cardiac surgery. Mayo Clinic researchers evaluated compliance with American College of Cardiology/American Heart Association guidelines for w[...] Sept. 27, 2023 Incidence and burden of tricuspid regurgitation in patients with atrial fibrillation AF is a risk factor for isolated TR in absence of other known etiologies. A Mayo Clinic study examined the incidence and impact of clinically significant isolated TR in AF. Aug. 15, 2023 Advanced heart failure complexities and when to refer for specialty care Daniel S. Yip, M.D., a Mayo Clinic transplant cardiologist, responds to questions about pinpointing heart failure status and when to consider referral for advanced heart failure care. May 06, 2023 Now available: Mayo Clinic ventricular tachycardia calculator Mayo Clinic now offers a practical diagnostic solution that does not require a high level of electrocardiogram interpretation expertise: the Mayo Clinic ventricular tachycardia calculator. April 29, 2023 53-year-old man with progressive dyspnea A case study, published in Mayo Clinic Proceedings, discusses a 53-year-old man with a history of cardiovascular issues who was admitted to Mayo Clinic for management of progressive dyspnea. April 29, 2023 Mayo Clinic Children's Center specialists perform center's first pediatric transplant with heart-in-a-box technology Mayo Clinic Children's Center specialists perform the center's first pediatric transplant with heart-in-a-box technology. March 15, 2023 Identifying at-risk patients to minimize complications Postoperative atrial fibrillation (POAF) is one of the most common complications after cardiac surgery. A retrospective Mayo Clinic study identified patients at a higher risk of complications to minimize the occurrence [...] Feb. 24, 2023 Carotid plaque imaging spurs innovative care Advanced technology allows Mayo Clinic neuroradiologists to assess specific plaque features as well as the degree of luminal stenosis, for improved management of carotid artery disease. Jan. 28, 2023 Science Saturday: Mayo researchers streamline genetic testing in heart failure clinic, improve clinical care In a new study published in Genetics in Medicine, Mayo Clinic researchers streamlined genetic testing and counseling for patients with dilated cardiomyopathy, a type of heart muscle disease that causes the heart chambers ([...] Dec. 16, 2022 First-in-state transplant using "heart-in-a-box" perfusion system performed at Mayo Clinic in Arizona Specialists at the Mayo Clinic campus in Arizona performed the first heart transplant in the state using a new perfusion system that improves sustenance of donor hearts, allowing more patients to receive heart transplan[...] Nov. 19, 2022 Science Saturday: Novel suppression-replacement preclinical gene therapy study shows promise in long and short QT syndromes In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long Q[...] Nov. 15, 2022 20-year review suggests athletes with genetic heart disease may return safely to competitive sports Mayo Clinic researchers conducted a review of athletes who were treated at Mayo during a 20-year period, and their findings suggest that after the patient's condition has been properly evaluated and treated, an athlete'[...] Nov. 14, 2022 AI transforms smartwatch ECG signals into a diagnostic tool for heart failure Two health tech advances are at the heart of a study published in Nature Medicine: an app and backend infrastructure to let patients remotely share smartwatch ECG data with their clinicians in an easy and secure way, and t[...] Nov. 01, 2022 High adopters of AI-enabled screening tool are more likely to diagnose left ventricular dysfunction than low adopters, Mayo Clinic study finds ROCHESTER, Minn. — Artificial intelligence can improve diagnosis and treatment for patients, but first the AI-enabled clinical tools have to be easily available and used. New research from Mayo Clinic finds that clinicians[...] Nov. 01, 2022 Clinician adoption of an artificial intelligence algorithm to detect Left ventricular systolic dysfunction in primary care To better understand the complexities of artificial intelligence (AI) adoption in the clinical setting, this study compares clinician- and patient-level characteristics of those more likely to respond to the prompted re[...] Oct. 20, 2022 Pediatric ventricular arrhythmia in a normal heart Pediatric patients with known heart conditions may be at risk of ventricular arrhythmia and require a different approach compared with patients with ventricular arrhythmia and normal hearts. Oct. 11, 2022 Management of patients with post-acute sequelae of SARS-CoV-2 (PASC) Experts from the American Academy of Physical Medicine and Rehabilitation (AAPM&R) summarize the current understanding of post-acute sequelae of SARS-CoV-2 (PASC), also called long COVID-19, and associated cardiovas[...] Sept. 28, 2022 AI-guided screening uses ECG data to detect a hidden risk factor for stroke An AI-guided targeted screening strategy is effective in detecting new cases of atrial fibrillation that would not have come to attention in routine clinical care. This strategy could reduce the number of undiagnosed cases[...] Sept. 27, 2022 Ross procedure a durable option for children with aortic valve disease This complex surgical procedure offers children a longer timespan between interventions and gives them a higher quality of life. Sept. 21, 2022 Preventing recurrent ischemic stroke The Heart Brain Clinic brings together neurologists and cardiologists to determine stroke etiology. Patients see both types of specialists during the same half-day visit. Aug. 25, 2022 Amyloidosis, the heart transplant precursor to keep on your diagnostic radar Amyloidosis is not only complex to diagnose but until recently, it was considered fatal. A Mayo Clinic transplant cardiologist explains Mayo Clinic's approach to this disease, including transplant for advanced disease. Aug. 01, 2022 Tricuspid regurgitation impact on outcomes (TRIO): A simple clinical risk score The purpose of this retrospective study was to determine which clinical variables infer the highest risk of mortality in patients with notable tricuspid regurgitation and develop a clinical assessment tool. July 29, 2022 Geographical allocation changes boost heart and lung transplant program at Mayo Clinic in Minnesota An expanded geographical reach with the 2017 to 2018 U.S. heart and lung transplant allocation changes has prompted significant program expansion at Mayo Clinic's Minnesota campus. July 01, 2022 Women with cardiovascular disease in pregnancy receive multidisciplinary care Women with all types of cardiovascular disease receive comprehensive care during pregnancy, from preconception counseling to postpartum follow-up and risk factor assessment. March 31, 2022 Expertise in the nuances of diagnosis, management and surgery for vascular rings Specialists developed an algorithm to evaluate patient risk, best age for surgery and when birth should occur at hospitals equipped for pediatric heart surgery to correct vascular rings. March 31, 2022 New protocols expand donor pool for highly sensitized pediatric patients receiving heart transplants Use of induction immunosuppression and removal of antibodies that could affect donor hearts allow use of hearts that historically may have been contraindicated. March 31, 2022 Surgery for hypertrophic cardiomyopathy benefits pediatric patients Surgical myectomy produces greater late survival and a better quality of life than the expected survival of pediatric patients with obstruction treated with medical therapy alone. March 31, 2022 Innovative endovascular band placement may eliminate or delay surgery for infants with congenital heart disease Endovascular band placement regulates blood flow to the lungs, avoiding or delaying surgery for infants with congenital heart disease. March 31, 2022 New physician guidelines to identify patients at risk of sudden cardiac death Updated guidelines help primary care physicians and pediatric cardiologists identify and treat patients at risk of sudden cardiac death. Jan. 14, 2022 Artificial intelligence can identify patients at risk of atrial fibrillation and heart failure in Graves' disease Artificial intelligence (AI) helps identify patients with Graves' disease who are at increased risk of developing atrial fibrillation (AF) and heart failure and who may benefit from closer surveillance. Sept. 24, 2021 Aortic stenosis severity underestimated when mean gradient is obtained during atrial fibrillation Research on the significance of high transvalvular gradients in atrial fibrillation low-gradient aortic stenosis indicates aortic stenosis severity is underestimated when the mean gradient is obtained during atrial fibr[...] Aug. 27, 2021 Mayo Clinic in Florida: First hospital in the world to use a new heart pump as bridge to transplant Mayo Clinic in Florida is the only hospital internationally using the new Impella 5.5 heart pump as a bridge to transplant. The pump offers numerous advantages over the left ventricular assist device. Aug. 17, 2021 Order is everything: New procedure for heart-liver transplant averts rejection risk A Mayo Clinic study published in Journal of the American College of Cardiology shows transplanting the liver first in a heart-liver transplant significantly decreases rejection rates for highly sensitized patients. Aug. 11, 2021 Organ perfusion systems a boon to heart and lung transplants Transplant specialists at Mayo Clinic in Florida use organ perfusion systems for some heart and lung transplants, resulting in multiple advantages for recipients — including saving lives. July 09, 2021 Beyond Stem Cells, Regenerative Medicine Finds Exosomes Researchers studying the difference between responders and nonresponders to stem cell therapy found a crucial difference in the types of exosomes released by highly regenerative stem cells. Nov. 26, 2020 Drug use impacts the care required by patients with infective endocarditis A study of nearly 35,000 heart valve surgeries indicates that in some regions of the U.S., drug use-associated infective endocarditis now constitutes a majority of infective endocarditis valve surgeries. Nov. 26, 2020 Congenital cardiac surgery: What's next? Mayo Clinic's congenital cardiac surgery specialists provide corrective care for many patients with congenital heart disease. These patients live with an excellent quality of life into adulthood. Nov. 26, 2020 TAILOR-PCI narrowly misses primary goal but indicates intriguing trends The TAILOR-PCI trial explores whether anti-platelet therapy guided by CYP2C19 genetic metabolizer status could reduce the incidence of ischemic events after percutaneous coronary intervention. Oct. 03, 2020 MitraClip treatment of mitral regurgitation after cardiac transplant: Case report A 72-year-old male who underwent orthotopic cardiac transplantation received MitraClip placement for severe mitral regurgitation, with almost complete resolution of symptoms within weeks of implantation. Oct. 03, 2020 New and novel treatments for hyperlipidemia Clinical outcome trials study the use of human monoclonal antibodies to target biochemical pathways that impact LDL receptor availability and monoclonal antibodies to block the PCSK-9 protein. Aug. 21, 2020 Cardio-oncology — A marriage of cardiology & oncology With more cancer drug options and increased treatment success, patients with cancer are surviving in record numbers. To address negative side effects of therapies on the heart and vascular function, Mayo Clinic establis[...] Feb. 01, 2020 Earlier intervention may improve outcomes in patients with aortic valve regurgitation Researchers report that patients had a higher mortality once they developed symptoms, and aortic valve surgery should be considered at an earlier stage of left ventricular enlargement. Feb. 01, 2020 Does reduction in red meat consumption improve health? Mayo specialists who reviewed recent studies from the NutriRECS consortium recommend, based on the totality of trial evidence, continuing to adhere to current dietary guidelines. Feb. 01, 2020 Modified immunosuppressive regimen improves survival in heart transplant patients Retrospective research shows that early conversion from a calcineurin inhibitor-based regimen to sirolimus lowers rates of cardiac allograft vasculopathy and malignancy in heart transplant recipients. Nov. 27, 2019 Heart Brain Clinic targets cryptogenic stroke The Mayo Clinic Heart Brain Clinic is a leading collaborative specialty care model for managing and preventing cryptogenic strokes. Aug. 03, 2019 Cone reconstruction for Ebstein anomaly Mayo Clinic heart surgeons pioneered the cone reconstruction technique to correct Ebstein anomaly. Outcome data shows the technique is safe, durable and effective. Aug. 03, 2019 Pulmonary valve replacement the optimal treatment for asymptomatic patient with repaired tetralogy of Fallot Mayo Clinic cardiologists determined pulmonary valve replacement was the appropriate treatment for a 32-year-old, asymptomatic patient with a history of tetralogy of Fallot and severe pulmonary regurgitation. June 01, 2019 Coronary anomaly clinic at Mayo Clinic A specialized subclinic of clinical cardiologists, cardiac imaging specialists and cardiovascular surgeons is devoted to the care and understanding of anomalies of the coronary arteries. June 01, 2019 Concomitant mitral valve intervention may increase risk for patients with hypertrophic cardiomyopathy undergoing septal myectomy A retrospective study supports the need for increasing surgical experience with septal myectomy for obstructive hypertrophic cardiomyopathy to further improve outcomes. June 01, 2019 Myocarditis biomarker predicts severity A research collaboration led by Mayo Clinic investigators identified the first biomarker for myocarditis, sera soluble ST2, and found it significantly elevated in men ≤ 50 years, compared with healthy controls and wo[...] June 01, 2019 Artificial intelligence-enabled ECG screening for asymptomatic left ventricular dysfunction Mayo researchers use convolutional neural networks to analyze electrocardiograms for silent subclinical, metabolic or structural abnormalities that may predict the presence of asymptomatic left ventricular dysfunction. Feb. 13, 2019 New tool predicts myocarditis-related heart failure in men Researchers found elevated levels of a protein in the blood, soluble ST2, to be a predictor of heart failure in men under 50 with myocarditis. Feb. 01, 2019 Congenital heart disease: The first 50 years … the next 50 years Congenital heart disease interventions are evolving due to the adult congenital heart disease subspecialty, improvement in transcatheter valve prostheses and imaging techniques, demand for cardiac replacement, and stem [...] Feb. 01, 2019 3D printing: The next dimension in cardiac imaging Mayo specialists use 3D printing to plan, explain and manage treatment for patients with congenital heart disease and teach complex cardiac anatomy effectively. Dec. 12, 2018 High-sensitivity troponin assay promises novel uses in managing patients with chronic heart disease FDA-approved assays T Gen 5 and hsTnI detect even the smallest rise in troponin levels, allowing for faster recognition of acute myocardial infarction and heart attack. Sept. 06, 2018 Multidisciplinary care and smooth transitions for children with congenital heart disease State-of-the-art echocardiography and expertise in complex cardiac conditions help Mayo specialists diagnose and treat patients with congenital heart disease. For patients who need heart transplantation, a Mayo protocol[...] Aug. 22, 2018 Mayo Clinic launches Cardiac Sarcoidosis Clinic Specialists at Mayo Clinic's Cardiac Sarcoidosis (CS) Clinic collaborate to provide innovative approaches to the diagnosis and management of patients with suspected or clinically definite cardiac sarcoidosis. Resea[...] May 04, 2018 Stroke reduction in nonvalvular atrial fibrillation with the left atrial appendage closure device: an update Left atrial occlusion devices provide a treatment option for patients at significant risk of thromboembolic stroke for whom long-term anticoagulation is either contraindicated or felt to be suboptimal. Jan. 25, 2018 Using Statin Choice Decision-Aid tool and laboratory testing to reduce cardiac risk The Mayo Clinic Statin Choice Decision-Aid tool helps clinicians have meaningful conversations with their patients about whether they should use statins to reduce their risk of cardiovascular disease. April 10, 2017 Do frail individuals benefit from heart surgery? Researchers comparing health, well-being, and quality of life between frail and nonfrail patients with aortic valve stenosis before and after valve replacement surgery found that individuals deemed frail before surgery [...] Sept. 29, 2016 Team approach to valve-in-valve therapy: Innovations in treatment of bioprosthetic systemic AV valve dysfunction Mayo's structural heart team provides comprehensive care to patients who have previously undergone surgery to replace the mitral or tricuspid valve with a tissue bioprosthesis. Existing dysfunctional bioprosthetic valve[...] May 24, 2016 Marfan syndrome and related disorders Effective treatment has resulted in longer lives for patients with Marfan syndrome. Their care involves lifelong monitoring of cardiovascular health and management of noncardiovascular problems. May 24, 2016 The Heart Brain Clinic: Optimal team-based coordinated care The Heart Brain Clinic provides multidisciplinary evaluations to patients with neurological symptoms that may be attributable to a cardiac etiology such as patent foramen ovale or atrial fibrillation. April 01, 2016 Spontaneous coronary artery dissection: Hidden in plain sight The presentation of spontaneous coronary artery dissection (SCAD) mimics other acute coronary events. At Mayo Clinic, patients with SCAD undergo comprehensive vascular imaging; 66 percent of this population has evidence[...] April 01, 2016 Coronary artery calcium score: Are we doing too many or too few? Mayo clinicians who specialize in cardiovascular disease prevention believe that a coronary artery calcium score (CACS) can add valuable clinical information in selected patients. Nov. 20, 2015 Prosthetic valve thrombosis: Time is critical Anticoagulant therapy with warfarin with a goal INR of 2 to 3 is effective in treating tissue valve thrombosis in most patients. Cardiac valve replacement and the risk of thrombosis are increasingly common in aging popu[...] Nov. 20, 2015 PCSK9 inhibition: A game changer in cholesterol management PCSK9 inhibitors fill a therapeutic niche for patients with familial hypercholesterolemia or patients with statin intolerance who are not able to achieve the desired LDL-C level with conventional treatments. May 20, 2015 Heart failure with preserved ejection fraction (HFpEF): More than diastolic dysfunction Mayo Clinic studies test acute inhaled sodium nitrite compared with placebo in people who have heart failure with preserved ejection fraction (HFpEF) and rate adaptive atrial pacing in people with HFpEF and chronotropic[...] Jan. 27, 2015 Arm ergometer provides alternative to conventional stress testing Arm ergometer exercise testing can be performed with the patient standing or seated and with or without oxygen consumption measurement. It is helpful for patients with paraplegia or symptoms that occur only during arm w[...] Nov. 21, 2014 Leadless pacing available for selected patients The Nanostim leadless pacemaker and the Micra transcatheter pacing system are implanted directly into the right ventricular apex. Nov. 21, 2014 Percutaneous therapy offers new option for treatment of mitral regurgitation Patient experience with the MitraClip device, which fixes the anterior and posterior mitral leaflets together under transesophageal echocardiographic (TEE) guidance to treat mitral regurgitation, has been favorable, wit[...] Oct. 23, 2014 Endovascular repair of complex aortic aneurysms Fenestrated and branched stent-grafts may provide a safe, effective technique for endovascular repair of aneurysms involving the visceral arteries. Studies indicate a high technical success and a low risk of complicatio[...] April 16, 2014 Role of cardiac MRI in the assessment of cardiac amyloidosis Role of cardiac MRI in the assessment of cardiac amyloidosis — Although biopsy is still the gold standard of diagnosis for patients with suspected cardiac amyloidosis, noninvasive cardiac MRI offers superior abili[...] April 16, 2014 Investigators identify mortality risk factors in apical hypertrophic cardiomyopathy Investigators identify mortality risk factors in apical hypertrophic cardiomyopathy — Kaplan-Meier analysis of 2,662 patients with hypertrophic cardiomyopathy evaluated at Mayo Clinic indicates that predictors of [...] Medical Professionals Cardiovascular Diseases & Cardiac Surgery News