Diphtheria, Tetanus, And Acellular Pertussis Vaccine (Intramuscular Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

1. Collapse or shock-like state
2. crying for 3 hours or more
3. fever over 102.2 °F
4. redness or swelling of 4 inches or more at the injection site
5. seizures
6. severe pain at the injection site

Incidence not known

1. Agitation
2. back pain
3. black, tarry stools
4. bleeding gums
5. bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
6. blood in the urine or stools
7. bloody nose
8. bluish color of the fingernails, lips, skin, palms, or nail beds
9. blurred vision
10. chest tightness
11. confusion
12. cough
13. diarrhea
14. difficulty with swallowing
15. dizziness
16. drowsiness
17. fast heartbeat
18. hallucinations
19. headache
20. hoarseness
21. irritability
22. irritation
23. joint pain, stiffness, or swelling
24. loss of bladder control
25. loss of consciousness
26. loss of strength or energy
27. muscle pain or weakness
28. nausea and vomiting
29. pain or cramping in the abdomen or stomach
30. pinpoint red spots on the skin
31. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
32. rash with flat lesions or small raised lesions on the skin
33. screaming
34. sleepiness or unusual drowsiness
35. sneezing
36. sore throat
37. stiff neck
38. swollen, painful, or tender lymph glands in the neck, armpit, or groin
39. total body jerking
40. trouble breathing
41. unusual bleeding or bruising
42. unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Fever of 99.5 °F or more
2. fussiness
3. loss of appetite
4. mild pain, redness, swelling, or tenderness at the injection site
5. restlessness
6. weight loss

Incidence not known

1. Crying
2. ear pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: May 01, 2024

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