Before Using

Drug information provided by: Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of tranylcypromine in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of tranylcypromine in geriatric patients. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving tranylcypromine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Amitriptyline
  • Amoxapine
  • Amphetamine
  • Apraclonidine
  • Atomoxetine
  • Benzphetamine
  • Brimonidine
  • Bupropion
  • Buspirone
  • Carbamazepine
  • Carbinoxamine
  • Citalopram
  • Clomipramine
  • Clovoxamine
  • Cyclobenzaprine
  • Cyproheptadine
  • Desipramine
  • Desvenlafaxine
  • Dexfenfluramine
  • Dexmethylphenidate
  • Dextroamphetamine
  • Dextromethorphan
  • Diethylpropion
  • Dopamine
  • Dothiepin
  • Doxepin
  • Doxylamine
  • Duloxetine
  • Epinephrine
  • Escitalopram
  • Femoxetine
  • Fenfluramine
  • Fluoxetine
  • Fluvoxamine
  • Furazolidone
  • Guanadrel
  • Guanethidine
  • Imipramine
  • Isocarboxazid
  • Isometheptene
  • Levodopa
  • Levomethadyl
  • Levomilnacipran
  • Linezolid
  • Lisdexamfetamine
  • Lofepramine
  • Maprotiline
  • Mazindol
  • Meperidine
  • Mephentermine
  • Methamphetamine
  • Methotrimeprazine
  • Methyldopa
  • Methylene Blue
  • Methylphenidate
  • Milnacipran
  • Mirtazapine
  • Nefopam
  • Nortriptyline
  • Opipramol
  • Pargyline
  • Paroxetine
  • Phendimetrazine
  • Phenelzine
  • Phenmetrazine
  • Phentermine
  • Phenylalanine
  • Phenylephrine
  • Phenylpropanolamine
  • Procarbazine
  • Protriptyline
  • Pseudoephedrine
  • Rasagiline
  • Reserpine
  • Rizatriptan
  • Selegiline
  • Sertraline
  • Sibutramine
  • Sumatriptan
  • Tapentadol
  • Tetrabenazine
  • Tranylcypromine
  • Trazodone
  • Trimipramine
  • Tryptophan
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Zolmitriptan

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Albuterol
  • Altretamine
  • Arformoterol
  • Avocado
  • Bambuterol
  • Bitter Orange
  • Clenbuterol
  • Colterol
  • Difenoxin
  • Diphenoxylate
  • Disulfiram
  • Droperidol
  • Entacapone
  • Ephedrine
  • Ethchlorvynol
  • Fenoterol
  • Fentanyl
  • Formoterol
  • Frovatriptan
  • Guarana
  • Hexoprenaline
  • Hydrocodone
  • Hydromorphone
  • Indacaterol
  • Iobenguane I 123
  • Isoetharine
  • Kava
  • Levalbuterol
  • Licorice
  • Lorcaserin
  • Ma Huang
  • Mate
  • Metaproterenol
  • Metaraminol
  • Methoxamine
  • Metoclopramide
  • Morphine
  • Morphine Sulfate Liposome
  • Nefazodone
  • Oxycodone
  • Pirbuterol
  • Procaterol
  • Reboxetine
  • Reproterol
  • Ritodrine
  • Salmeterol
  • St John's Wort
  • Tegafur
  • Terbutaline
  • Tolcapone
  • Tramadol
  • Tretoquinol
  • Tulobuterol
  • Tyrosine
  • Vilanterol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acarbose
  • Acetohexamide
  • Benfluorex
  • Chlorpropamide
  • Ginseng
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Guar Gum
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Metformin
  • Miglitol
  • Repaglinide
  • Tolazamide
  • Tolbutamide
  • Troglitazone

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco.

  • Caffeine
  • Tyramine Containing Food

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bipolar disorder (manic-depressive illness) or
  • Headache, history of or
  • Heart or blood vessel disease or
  • Hypertension (high blood pressure) or
  • Liver disease, history of or
  • Pheochromocytoma (an adrenal problem) or
  • Stroke, history of—Should not be used in patients with these conditions.
  • Diabetes or
  • Hyperthyroidism (overactive thyroid or
  • Hypotension (low blood pressure)—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.