Proper Use

Drug information provided by: Micromedex

Take this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Topiramate may be taken with or without food.

Swallow the extended-release capsule whole. Do not open, crush, or chew the capsule. Avoid drinking alcohol for 6 hours before and 6 hours after taking the Trokendi XR™ capsule.

Swallow the tablet whole. Do not break, crush, or chew it. The tablet may taste bitter if it is held in the mouth or chewed.

The sprinkle capsule may be swallowed whole or opened and sprinkled on a small amount (1 teaspoon) of soft food like applesauce. Swallow the food mixture immediately without chewing. Do not store the mixture for use at a later time.

Drink extra water with this medicine to help prevent kidney stones.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (extended-release capsules):
    • For seizures (taken with other medicines):
      • Adults—At first, 25 or 50 milligrams (mg) once a day. Your doctor may adjust the dose as needed. However, the dose is usually not more than 400 mg per day.
      • Children 6 years of age and older—At first, 25 milligrams (mg) once a day in the evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 5 to 9 mg per kilogram (kg) of body weight per day.
      • Children younger than 6 years of age—Use is not recommended.
    • For seizures (taken alone):
      • Adults, teenagers, and children 10 years of age and older—At first, 50 milligrams (mg) once a day. Your doctor may adjust the dose as needed. However, the dose is usually not more than 400 mg per day.
      • Children younger than 10 years of age—Use and dose must be determined by your doctor.
  • For oral dosage forms (capsules or tablets):
    • For seizures (taken with other medicines):
      • Adults—At first, 25 or 50 milligrams (mg) once a day. Your doctor may adjust the dose as needed. However, the dose is usually not more than 400 mg per day.
      • Children 2 years of age and older—At first, 25 milligrams (mg) once a day in the evening. Your doctor may adjust the dose as needed.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
    • For seizures (taken alone):
      • Adults, teenagers, and children 10 years of age and older—At first, 50 milligrams (mg) per day, divided and taken as 2 doses. Your doctor may adjust the dose as needed. However, the dose is usually not more than 400 mg per day.
      • Children 2 to 10 years of age—At first, 25 milligrams (mg) once a day in the evening. Your doctor may adjust the dose as needed.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
    • For migraine headaches:
      • Adults—At first, 25 milligrams (mg) once a day in the evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 100 mg per day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.