Proper Use

Drug information provided by: Micromedex

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking first with your doctor.

This medicine should come with a Medication Guide. Read and carefully follow the instructions before starting treatment and each time you get a refill. Ask your doctor or pharmacist if you have any questions.

It is important that this medicine be taken with food. Take the capsule or tablet within 2 hours after a meal.

Saquinavir capsules or tablets (Invirase®) should always be taken together, and at the same time, with ritonavir (Norvir®). Take all other medicines your doctor has prescribed at the right time of day.

If you are not able to swallow the capsule, open the capsule and pour the contents in an empty container. Add 15 mL (about 1/2 ounce) of sugar syrup or sorbitol syrup or 3 teaspoons of jam to the container. Stir for 30 to 60 seconds and let the mixture come to room temperature. Drink or eat the entire mixture to get the full dose.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (capsules or tablets):
    • For treatment of HIV infection:
      • For patients who have not taken HIV medicines:
        • Adults and children 16 years and older—At first, 500 milligrams (mg) with ritonavir 100 mg two times a day, taken for 7 days. Then, your doctor will increase your dose to 1000 mg with ritonavir 100 mg two times a day.
        • Children younger than 16 years—Use and dose must be determined by your doctor.
      • For patients switching from another ritonavir or NNRTI-containing regimen:
        • Adults and children 16 years and older—At first, 1000 milligrams (mg) (5 capsules or 2 tablets) taken with ritonavir 100 mg two times a day.
        • Children younger than 16 years—Use and dose must be determined by your doctor.
      • For patients switching from delavirdine or rilpivirine-containing regimen:
        • Adults and children 16 years and older—At first, 500 milligrams (mg) with ritonavir 100 mg two times a day, taken for 7 days.
        • Children younger than 16 years—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.