Precautions

Drug information provided by: Micromedex

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests will be needed to check for unwanted effects.

It is important to tell your doctor if you become pregnant. Your doctor may want you to join a pregnancy registry for patients receiving this medicine.

Using this medicine for a long time may cause changes in your bone marrow. These changes may lead to a serious condition called bone marrow fibrosis, where your body produces less blood cells. Your doctor will check for this unwanted effect.

Blood clotting problems may occur while you are receiving this medicine. Check with your doctor right away if you have pain, swelling, or tenderness in your leg, or shortness of breath and pain in your chest.

Do not stop receiving this medicine without checking first with your doctor. Stopping this medicine suddenly may cause the number of platelets to go below the number you had before you started receiving the medicine. This will increase your risk for bleeding. Your doctor will check your platelet levels and progress when you stop receiving the medicine.

Portal vein thrombosis (a blood clotting problem) occurs in patients receiving this medicine. It usually occurs in patients with low platelet counts caused by liver problems (including cirrhosis). Check with your doctor right away if you have abdominal or stomach pain, blood in the stool, or if you are vomiting blood.