Drug information provided by: Micromedex

If you experience signs and symptoms of high blood pressure, you should seek immediate medical attention. Signs and symptoms include severe headache, blurred vision or visual disturbances, difficulty thinking, stupor or coma, seizures, chest pain, unexplained nausea or vomiting, or signs and symptoms of a stroke .

You should not use any of the following medicines while you are taking rasagiline, or for 2 weeks after stopping rasagiline:

  • Analgesic agents (methadone [e.g., Methadose] propoxyphene [e.g., Darvon], tramadol [e.g., Ultram]) or
  • Cold products containing ephedrine, phenylephrine, phenylpropanolamine, or pseudoephedrine or
  • Cyclobenzaprine (e.g., Flexeril) or
  • MAO inhibitors or
  • Meperidine (e.g., Demerol) or
  • Mirtazapine (e.g., Remeron)

You should tell your doctor before having any surgery that requires general anesthesia. Rasagiline should be discontinued at least 14 days before surgery .

Some studies have shown that patients with Parkinson's disease may have a higher risk of developing skin cancer. Therefore, it is very important that a dermatologist check you at regular visits for melanomas. You or your caregiver should also monitor for melanomas frequently and on a regular basis .

If you are taking this medicine with levodopa, you may experience increased dyskinesia (e.g., twitching, twisting, uncontrolled repetitive movements of tongue, lips, face, arms, or legs) and postural low blood pressure (e.g., chills, cold sweats, confusion, dizziness, faintness, or light-headedness when getting up from lying or sitting position).