Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Botox
  2. Botox Cosmetic


OnabotulinumtoxinA is used to treat certain eye conditions, such as blepharospasm (a condition where the eyelid will not stay open because of a muscle spasm) or strabismus (a condition where the eyes do not line up properly). This medicine is also used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck) and some types of axillary hyperhidrosis (severe sweating of the armpits). It is used for increased muscle stiffness in the elbow, wrist, and finger muscles in adults with upper limb spasticity. It is also used to prevent headaches in patients with chronic migraine (severe headaches for 15 or more days a month lasting 4 or more hours a day). OnabotulinumtoxinA is used cosmetically to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines) and crow's feet lines around the eyes (lateral canthal lines). It is also used to treat urinary incontinence (loss of bladder control) in patients with an overactive bladder caused by nervous system disorders (eg, multiple sclerosis, spinal cord injury). It is also used to treat overactive bladder with symptoms such as loss of bladder control, increased urge to urinate, and frequent need to urinate in patients who have failed treatment with other medicines.

OnabotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.

OnabotulinumtoxinA is injected into the muscles that are affected. Depending on your condition, more than one treatment may be required.

This medicine is available only with your doctor's prescription and will be administered by your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, onabotulinumtoxinA is used in certain patients with the following medical conditions:

  • Frey's syndrome or gustatory sweating (red areas and sweating on the cheeks and ears after eating).
  • Palmar and plantar hyperhidrosis (severe sweating of the palms and feet).
  • Spasms of the arms in stroke patients.
  • Spasms of the face.
  • Spasms of the feet and hands, including writer's cramp.
  • Spasms of the arms and legs in patients with multiple sclerosis.

This product is available in the following dosage forms:

  • Powder for Solution