Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Priorix® injection in infants younger than 12 months of age. Safety and efficacy have not been established.

Use of M-M-R® II is not recommended in children younger than 12 months of age. Safety and efficacy have not been established for measles vaccine in children younger than 6 months of age and for mumps and rubella vaccine in children younger than 12 months of age.

Geriatric

Appropriate studies on the relationship of age to the effects of Priorix® and M-M-R® II injection have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of Priorix® injection in the elderly.

Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this vaccine with any of the following medicines is not recommended. Your doctor may decide not to use this vaccine or change some of the other medicines you take.

  • Alemtuzumab
  • Bendamustine
  • Bortezomib
  • Bosutinib
  • Cabazitaxel
  • Capecitabine
  • Carboplatin
  • Carfilzomib
  • Carmustine
  • Chlorambucil
  • Cisplatin
  • Cladribine
  • Clofarabine
  • Cyclophosphamide
  • Cytarabine
  • Cytarabine Liposome
  • Dacarbazine
  • Dasatinib
  • Daunorubicin
  • Daunorubicin Citrate Liposome
  • Daunorubicin Liposome
  • Deflazacort
  • Docetaxel
  • Doxorubicin
  • Epirubicin
  • Etoposide
  • Fludarabine
  • Fluorouracil
  • Gemcitabine
  • Gemtuzumab Ozogamicin
  • Hydroxyurea
  • Idarubicin
  • Ifosfamide
  • Imatinib
  • Interferon Alfa
  • Irinotecan
  • Irinotecan Liposome
  • Lomustine
  • Mechlorethamine
  • Melphalan
  • Mercaptopurine
  • Methotrexate
  • Mitomycin
  • Mitoxantrone
  • Nelarabine
  • Nilotinib
  • Ofatumumab
  • Oxaliplatin
  • Paclitaxel
  • Paclitaxel Protein-Bound
  • Pemetrexed
  • Pentostatin
  • Ponatinib
  • Procarbazine
  • Rituximab
  • Temozolomide
  • Teniposide
  • Thiotepa
  • Topotecan
  • Tositumomab
  • Vinblastine
  • Vinorelbine

Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Adalimumab
  • Anifrolumab-fnia
  • Ansuvimab-zykl
  • Antithymocyte Globulin Rabbit
  • Atoltivimab
  • Axicabtagene Ciloleucel
  • Azathioprine
  • Baricitinib
  • Belatacept
  • Betibeglogene Autotemcel
  • Bimekizumab-bkzx
  • Brexucabtagene Autoleucel
  • Brodalumab
  • Canakinumab
  • Certolizumab Pegol
  • Deucravacitinib
  • Dupilumab
  • Efgartigimod Alfa-fcab
  • Elivaldogene Autotemcel
  • Emapalumab-lzsg
  • Etanercept
  • Etrasimod
  • Everolimus
  • Fingolimod
  • Golimumab
  • Guselkumab
  • Hyaluronidase
  • Immune Globulin
  • Inebilizumab-cdon
  • Infliximab
  • Ixekizumab
  • Leflunomide
  • Leniolisib
  • Lovotibeglogene Autotemcel
  • Meningococcal Vaccine
  • Mirikizumab-mrkz
  • Mycophenolic Acid
  • Ocrelizumab
  • Ozanimod
  • Ponesimod
  • Rilonacept
  • Risankizumab-rzaa
  • Ritlecitinib
  • Rozanolixizumab-noli
  • Sarilumab
  • Satralizumab-mwge
  • Secukinumab
  • Siponimod
  • Sirolimus
  • Spesolimab-sbzo
  • Tacrolimus
  • Teplizumab-mzwv
  • Teriflunomide
  • Tildrakizumab-asmn
  • Tocilizumab
  • Tofacitinib
  • Trabectedin
  • Tralokinumab-ldrm
  • Ublituximab-xiiy
  • Upadacitinib
  • Ustekinumab
  • Valoctocogene Roxaparvovec-rvox
  • Vamorolone
  • Voclosporin

Receiving this vaccine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abatacept
  • Cytomegalovirus Immune Globulin, Human
  • Hepatitis B Immune Globulin
  • Rabies Immune Globulin
  • Respiratory Syncytial Virus Immune Globulin, Human
  • Tetanus Immune Globulin
  • Vaccinia Immune Globulin, Human
  • Varicella-Zoster Immune Globulin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to eggs, history of—May increase risk for a serious allergic reaction to occur again.
  • Immune system problems—Use with caution. This condition may decrease the useful effects of the vaccine.
  • Immune system problems, severe or
  • Tuberculosis, active and untreated—Should not be used in patients with this condition.