Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine usually comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Carefully follow the special meal plan your doctor gave you. This is the most important part of controlling your diabetes, and is necessary if the medicine is to work properly. Exercise regularly and test for sugar in your blood or urine as directed.

Take this medicine with meals.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (extended-release tablets):
    • For type 2 diabetes:
      • Adults:
        • Patients taking metformin alone—The metformin dose is the same as the dose you are already taking plus 5 milligrams (mg) of linagliptin. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 5 mg of linagliptin and 2000 mg of metformin once a day.
        • Patients taking linagliptin alone—At first, one tablet containing 5 mg of linagliptin and 1000 mg of metformin once a day. Your doctor may gradually increase your dose until your blood sugar is controlled. However, the dose is usually not more than 5 mg of linagliptin and 2000 mg of metformin once a day.
        • Patients taking linagliptin and metformin as separate components or Jentadueto® tablets—The metformin dose is the same as the dose you are already taking plus 5 mg of linagliptin. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 5 mg of linagliptin and 2000 mg of metformin once a day.
      • Children—Use and dose must be determined by your doctor.
  • For oral dosage form (tablets):
    • For type 2 diabetes:
      • Adults:
        • Patients taking metformin alone—The metformin dose is the same as the dose you are already taking. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 2.5 milligrams (mg) of linagliptin and 1000 mg of metformin 2 times a day.
        • Patients taking linagliptin alone—At first, 1 tablet containing 2.5 mg of linagliptin and 500 mg of metformin 2 times a day. Your doctor may gradually increase your dose until your blood sugar is controlled. However, the dose is usually not more than 2.5 mg of linagliptin and 1000 mg of metformin 2 times a day.
        • Patients taking linagliptin and metformin as separate components—The linagliptin and metformin dose are the same as the dose you are already taking. Your doctor may adjust your dose until your blood sugar is controlled. However, the dose is usually not more than 2.5 mg of linagliptin and 1000 mg of metformin 2 times a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the tablets dry.

Portions of this document last updated: May 01, 2024

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