Proper Use

Drug information provided by: Micromedex

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Take this medicine with fat-containing foods such as butter, cheese pizza, eggs, peanut butter, or whole milk dairy products (eg, whole milk, cheese, yogurt).

To use the oral granules:

  • Shake the packet gently before opening it.
  • Open one packet and pour the contents into 1 teaspoon of cold soft food or liquid (eg, applesauce, pureed fruits or vegetables, yogurt, water, milk, or juice).
  • Mix the granules with the soft food or liquid.
  • After mixing, give this medicine to your child within 1 hour. Make sure all medicine is taken.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may cause the amount of medicine in the blood to be too high.

Do not eat Seville oranges (bitter or sour oranges) or drink Seville orange juice while taking this medicine. Seville oranges or juice may cause the amount of medicine in the blood to be too high.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (granules or tablets):
    • For cystic fibrosis:
      • Adults and children 6 years of age and older—150 milligrams (mg) every 12 hours, taken with fat-containing food.
      • Children 2 to 5 years of age and weighing 14 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually one 75 mg packet every 12 hours, taken with fat-containing food.
      • Children 2 to 5 years of age and weighing less than 14 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually one 50 mg packet every 12 hours, taken with fat-containing food.
      • Children younger than 2 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose, take it as soon as you can. If your next regular dose is less than 6 hours away, wait until then to use the medicine and skip the missed dose.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.