Before Using

Drug information provided by: Micromedex

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children are especially sensitive to the effects of insulin before puberty (the time when sexual changes occur). Therefore, low blood sugar may be especially likely to occur.

Use in teenagers is similar to use in older age groups. The insulin need may be higher during puberty and lower after puberty.

Geriatric

Use in older adults is similar to use in other age groups. However, sometimes the first signs of low or high blood sugar are missing or not easily seen in older patients. This may increase the chance of low blood sugar during treatment. Also, some older people may have vision problems or other medical problems that make it harder for them to measure and inject the medicine. Special training and equipment may be needed.

Pregnancy

The amount of insulin you need changes during and after pregnancy. It is especially important for your health and your baby's health that your blood sugar be closely controlled. Close control of your blood sugar can reduce the chance of your baby gaining too much weight, having birth defects, or having high or low blood sugar. Be sure to tell your doctor if you plan to become pregnant or if you think you are pregnant.

Breastfeeding

Insulin does not pass into breast milk and will not affect the nursing infant. However, most women need less insulin while breast-feeding than they needed before. You will need to test your blood sugar often for several months in case your insulin dose needs to be changed.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alatrofloxacin
  • Balofloxacin
  • Ciprofloxacin
  • Clinafloxacin
  • Enoxacin
  • Fleroxacin
  • Flumequine
  • Gatifloxacin
  • Gemifloxacin
  • Grepafloxacin
  • Levofloxacin
  • Lomefloxacin
  • Metreleptin
  • Moxifloxacin
  • Norfloxacin
  • Ofloxacin
  • Pefloxacin
  • Prulifloxacin
  • Rufloxacin
  • Sparfloxacin
  • Temafloxacin
  • Tosufloxacin
  • Trovafloxacin Mesylate

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Changes in female hormones for some women (e.g., during puberty, pregnancy, or menstruation) or
  • High fever or
  • Infection, severe or
  • Mental stress or
  • Overactive adrenal gland, not properly controlled or
  • Other conditions that cause high blood sugar—These conditions increase blood sugar and may increase the amount of insulin you need to take, make it necessary to change the time when you inject the insulin dose, and increase the need to take blood sugar tests.
  • Diarrhea or
  • Gastroparesis (slow stomach emptying) or
  • Intestinal blockage or
  • Vomiting or
  • Other conditions that delay food absorption or stomach emptying—These conditions may slow the time it takes to break down and absorb your meal from your stomach or intestines, which may change the amount of insulin you need, make it necessary to change the time when you inject the insulin dose, and increase the need to take blood sugar tests.
  • Injury or
  • Surgery—Effects of insulin may be increased or decreased; the amount and type of insulin you need may change rapidly.
  • Kidney disease or
  • Liver disease—Effects of insulin may be increased or decreased, partly because of slower removal of insulin from the body; this may change the amount of insulin you need.
  • Overactive thyroid, not properly controlled—Effects of insulin may be increased or decreased, partly because of faster removal of insulin from the body. Until your thyroid condition is controlled, the amount of insulin you need may change, make it necessary to change the time when you inject the insulin dose, and increase the need to take blood sugar tests.
  • Underactive adrenal gland, not properly controlled or
  • Underactive pituitary gland, not properly controlled or
  • Other conditions that cause low blood sugar—These conditions lower blood sugar and may lower the amount of insulin you need, make it necessary for you to change the time when you inject the insulin dose, and increase the need to take blood sugar tests.