Proper Use

Drug information provided by: Merative, Micromedex®

A nurse or other trained health professional may give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot under your skin or into a vein.

Always double-check both the concentration (strength) of your insulin and your dose. Concentration and dose are not the same. The dose is how many units of insulin you will use. The concentration tells how many units of insulin are in each milliliter (mL), such as 100 units/mL (U-100), but this does not mean you will use 100 units at a time.

Each package of insulin lispro contains a patient information leaflet and patient instructions. Read this leaflet carefully and make sure you understand:

  • How to prepare the medicine.
  • How to inject the medicine.
  • How to use a disposable insulin delivery device.
  • How to use an external insulin pump.
  • How and when to change the infusion set, cartridge adapter, and insulin in the external insulin pump reservoir.
  • How and when to change the insulin lispro 3 mL cartridge.
  • How to dispose of syringes, needles, and injection devices.

It is best to use a different place on the body for each injection (eg, under the skin of your stomach, thigh, buttocks, or upper arm). Do not use the exact same spot for each injection. If you have questions about this, contact a member of your health care team.

Do not inject into skin areas that are tender, bruised, scaly, hard, damaged, thick, or has pits, lumps, or scars.

When used as a mealtime insulin, it should be taken within 15 minutes before a meal or immediately after a meal.

The insulin solution should look clear and colorless. Do not use insulin lispro if it is cloudy or thickened, discolored, or if there are particles in it. Do not mix this medicine with any other insulin. If you are told to mix lispro with a longer-acting insulin, draw up insulin lispro into the syringe first, then the longer-acting insulin. Inject it right away.

When used in an insulin pump: Carefully read and follow the external insulin pump instructions. This insulin should not be mixed with any other insulin or diluted when used in an insulin pump. The insulin lispro in the pump should be changed at least every 7 days and the infusion set and insertion site changed at least every 3 days. If you do not understand how you are to use the insulin pump or have concerns, contact your doctor or pharmacist.

Use a new needle for the Admelog® SoloStar® pen or prefilled pens each time you give yourself an injection. Always remove and throw the needle after each injection. Store the pen without a needle attached. Do not use the pen if it is broken or damaged.

Follow carefully the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.

Do not change the brand, type, or dose of your insulin unless your doctor tells you to. When you receive a new supply of insulin, check the label to be sure if it is the correct type of insulin.

Do not transfer Humalog® U-200 from the prefilled pen to a syringe for use.

To use the vial:

  • Wash your hands with soap and water.
  • Do not shake the vial.
  • Use only syringes that are made for insulin injections. Use a new syringe and needle each time you give yourself an injection.
  • Do not mix this medicine with any other insulin.

To use the Solostar® Prefilled Pen:

  • Wash your hands with soap and water.
  • Prime the pen by removing the air from the needle and cartridge. Select 2 units when turning the dose selector.
  • Press the injection button until it stops. You should see a "0" in the dose window.
  • You should see insulin at the needle tip. If you do not see insulin, repeat the priming steps but not more than 3 times. If there is still no insulin, change the needle and repeat the priming steps.
  • Turn the dose selector, be careful not to press the injection button.
  • You may see air bubbles in the insulin, which is normal.
  • Insert the needle into your skin and press the injection button all the way in for at least 10 seconds. Keep pressing until the needle has been pulled out from the skin. This will make sure that you have received the full dose.
  • Use a new needle each time you give yourself an injection. Always remove and throw the needle after each injection. Store the pen without a needle attached. Do not use the pen if it is broken or damaged.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For diabetes mellitus:
      • Adults and children 3 years of age and older—The dose is based on your blood sugar and must be determined by your doctor.
      • Children younger than 3 years of age—Use and dose must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store unused vials, pens, or cartridges in the refrigerator. Do not freeze. This medicine may be refrigerated for only 28 days. Throw the medicine away after the expiration date has passed.

The vial that you are currently using may be kept in the refrigerator or at room temperature in a cool place, away from direct heat and light, for up to 28 days.

The cartridge or pen that you are currently using should not be refrigerated. You should store the cartridge or pen at room temperature in a cool place, away from direct heat and light, for up to 28 days.

Throw away used syringes and needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.