Proper Use

Drug information provided by: Micromedex

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Your doctor may want you to take folic acid with this medicine.

Hydroxyurea should be handled with care. People who are not taking this medicine should avoid touching it. To decrease your chance of touching the medicine:

  • Wear disposable gloves when handling the bottle or capsules.
  • Wash your hands with soap and water before and after contact with the bottle or capsules.
  • Do not open the capsules. Avoid exposure to crushed or opened capsules.
  • If you touch an opened or crushed capsule, wash your skin right away with soap and water.
  • If powder from the capsule gets into your eyes, rinse them with water or an isotonic eyewash for 15 minutes.
  • If powder from the capsule is spilled, wipe it up right away with a damp disposable towel. Place the towel and the empty capsule in a closed container, such as a plastic bag.
  • The area where the powder spilled should be cleaned 3 times using a detergent solution followed by clean water.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For cancer of the head and neck:
      • Adults—Dose is based on body weight and must be determined by your doctor. The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For chronic myelocytic leukemia (CML):
      • Adults—Dose is based on body weight and must be determined by your doctor. The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For sickle cell anemia:
      • Adults—Dose is based on body weight and must be determined by your doctor. At first, the dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.