The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
Adults (18 years and older)
For diabetes, natural unprocessed honey has been taken by mouth in the following doses: 1 gram per kilogram daily for two weeks, then increased to 1.5 gram per kilogram daily for two weeks, then increased to 2 grams per kilogram for two weeks, and finally increased to 2.5 grams per kilogram for another two weeks. A dose of 0.5 milliliters per kilogram of Egyptian clover honey has been taken by mouth daily for 12 weeks.
For exercise performance, 8.8 milliliters per kilogram of a honey-sweetened drink (containing 110 milligrams of sodium per 240 milliliters), was taken by mouth 30 minutes before exercise and at the 10-minute halftime.
For dry mouth caused by radiation treatment, 5 milliliters of honey from wildflowers has been swished in the mouth for five minutes, then swallowed.
For malnutrition, 2 milliliters per kilogram of unprocessed polyfloral honey from Egypt has been diluted in water and taken by mouth daily in two divided doses, together with standard treatment, for two weeks.
For memory, 20 grams of tualang honey (Agro Mas) has been taken by mouth daily for 16 weeks.
For mouth sores caused by radiation treatment, 20 milliliters of honey rinse has been swished in the mouth for up to two minutes, then slowly swallowed, in the following regimens: 15 minutes before and 15 minutes after treatment, and six hours after radiation or at bedtime for up to seven weeks; or four times daily for four weeks of radiation treatment, plus two weeks afterward. Honey rinse has also been swished and spit out 15 minutes before and after radiation therapy, and at bedtime, for up to six weeks. A dose of 20 milliliters of Camellia sinensis honey has been applied to the irradiated areas for 15 minutes before treatment, 15 minutes after treatment, and 6 hours after treatment. Filtered honey or honey gauze (HoneySoft®) has been applied to the skin until healing.
For pneumonia, honey-thick liquid has been taken by mouth for three months.
For surgery, one teaspoon (5 milliliters) of honey has been taken by mouth every hour while awake for 14 days in combination with antibiotics and acetaminophen.
For wounds with pus-buildup, honey has been applied to the affected area, then covered with a honey dressing.
For burns, honey has been applied to the skin directly in doses of 15-30 milliliters every 1-2 days, and covered with a dry, sterile gauze or bandage. Honey has been applied to the skin as a dressing made from gauze filled with honey, and left in place for up to 25 days. Natural honey has been applied to burn wounds twice daily until complete healing.
For skin inflammation and dandruff, a diluted solution of honey and 90 percent warm water has been applied to the scalp for 2-3 minutes, then left for three hours.
For diabetic foot ulcers, a clean, non-sterile pure honey dressing has been applied to the skin daily, then covered with a sterile gauze and bandaged for 7-36 days. Non-sterile gauze filled with clover honey has been applied to the skin for up to three months or until the ulcer has healed.
For Fournier's gangrene, 15-30 milliliters of unprocessed honey has been applied to affected areas.
For high cholesterol, 70-75 grams of honey, sometimes dissolved in 250 milliliters of tap water, has been applied to the skin once daily for 14-30 days.
For catheter-related infections, 3 milliliters of Medihoney has been applied to the skin with each dressing change (three times weekly) until removal of the catheter.
For leg ulcers, 5 grams per 20 centimeters squared of Manuka honey dressing has been applied to the affected area weekly for four weeks. A calcium alginate dressing filled with Manuka honey has been applied for 12 weeks. A dose of 20 milliliters of unprocessed honey has been applied to each wound with each dressing, changed every two days, and given for up to five weeks or until the ulcer heals.
For parasites, a honey-soaked gauze dressing has been applied twice daily for up to six weeks.
For wounds after surgery, crude Yemini honey has been applied twelve times, once every hour, after initial washing.
For itching, a honey barrier cream has been applied to skin folds twice daily for 21 days.
For skin ulcers, multi-layer pressure bandages have been used over honey-filled dressings on the skin. Medihoney and manuka honey dressings have been applied to the skin for eight weeks.
For wound management, honey-filled dressings have been applied to the skin in doses of 20 milliliters of honey on a dressing pad. The following dressings have been applied to the skin: Activon Tulle, which is filled with 20-25 grams of Manuka honey, changed every 2-3 days for four weeks; sterile gauze dipped in unprocessed, undiluted honey; Honey-Soft, applied to wounds for up to 28 weeks; monofloral aloe honey, used on clean wounds once daily until healing; a manuka honey-filled alginate dressing applied twice weekly until healing; and Medihoney™ Antibacterial Wound Gel™, applied daily beginning 10 days after surgery.
For type 2 diabetes and high blood pressure, a 10 milliliter aqueous honey solution has been breathed deeply through the nose for up to 10 minutes. Honey solutions with 30-90 grams of natural, unprocessed honey with 250 milliliters of water have been inhaled.
For sinus infections, 2 milliliters of Manuka honey solution has been sprayed in the nostril once daily in the evening for 30 days.
For eye surgery, 25 percent honey eye drops have been used in the eyes five times daily for seven days before and five days after surgery in addition to Efflumidex®.
Children (under 18 years old)
For cough, 10 grams of eucalyptus honey, Labiatae honey, and citrus honey, and 17 milligrams per milliliter of buckwheat honey have been taken by mouth in single doses up to 30 minutes before bed. A dose of 2.5 milliliters of natural honey has been used as a single dose before bed.
For stomach flu, unprocessed, multifloral honey has been dissolved in oral rehydration solution (ORS) (5 milliliters per 100 milliliters of ORS) and taken by mouth within two hours of preparation.
For malnutrition, 2 milliliters per kilogram of pure, unprocessed multifloral honey solution (7.2 kilocalories per kilogram) plus standard treatment has been taken by mouth daily in two divided doses for two weeks.
For mouth sores caused by radiation treatment, 0.5-15 grams per kilogram of honey has been applied to affected areas three times daily for up to 10 days.
For infected wounds after surgery in newborns, 5-10 milliliters of unprocessed honey has been applied to the wound and covered with a sterile gauze dressing, which have been changed twice daily.
For wound healing, crude, undiluted honey-soaked gauze has been applied to wounds twice daily until healing.
This evidence-based monograph was prepared by The Natural Standard Research Collaboration