Proper Use

Drug information provided by: Micromedex

This medicine is given as a shot under your skin. Etanercept may sometimes be given at home to patients who do not need to be in the hospital. If you or your child are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand exactly how to use the medicine.

This medicine comes with a Medication Guide and a Patient Instructions for Use leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself or your child a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems.

This medicine is available in 3 forms. You may use a prefilled syringe, a prefilled SureClick™ autoinjector, or a vial (glass container).

The needle cap on the prefilled syringe and SureClick™ autoinjector contains dry natural rubber (a derivative of latex), which may cause allergic reactions in people who are sensitive to latex. Tell your doctor if you or your child have a latex allergy before you start using this medicine.

To use the autoinjector or syringe:

  • Wash your hands with soap and water before and after using this medicine.
  • Remove the carton with the syringe or autoinjector from the refrigerator and place it on a clean cloth.
  • Allow 30 minutes for the syringe or autoinjector to warm up to room temperature.
  • Do not remove the needle cover on the prefilled syringe or the autoinjector cap while allowing the medicine to reach room temperature. Remove these immediately before use.
  • Check the liquid in the syringe or autoinjector. It should be clear and colorless, and may have small white particles. If it is cloudy, discolored, or has large particles, do not use it.
  • Check that the amount of liquid in the prefilled syringe falls between the two purple fill level indicator lines on the syringe. If the syringe does not have the right amount of liquid, do not use it.
  • If the liquid is clear, place it on a clean, flat surface. Do not shake the medicine.
  • Choose an injection site on your body (e.g., thigh, abdomen or stomach area, or upper arm). Clean the injection site with a fresh alcohol wipe and let it dry.
  • Remove the cap or needle cover when you are ready to inject.
  • Do not inject into skin areas that are red, bruised, tender, or hard.
  • Throw away used needles in a hard, closed container (puncture-resistant) that the needles cannot poke through. Keep this container away from children and pets.

To use the vial:

  • Wash your hands with soap and water before and after using this medicine.
  • The vial of powder must be mixed with the liquid provided in your dose kit. Mix the medicine only when you are ready to use it. Do not shake the medicine after it has been mixed.
  • Do not use the mixture if it is cloudy or has particles floating in it.
  • If the liquid is clear, prepare your dose by filling the syringe with the proper amount from the vial. Attach a new needle to the syringe before you inject.
  • Choose an injection site on your body (e.g., thigh, abdomen or stomach area, or upper arm). Clean the injection site with a fresh alcohol wipe and let it dry.
  • Do not inject into skin areas that are red, bruised, tender, or hard.
  • Throw away used needles in a hard, closed container (puncture-resistant) that the needles cannot poke through. Keep this container away from children and pets.
  • If you are using one vial (container) for more than one dose, use the "Mixing Date" stickers from the dose kit to write the date you mixed the medicine. Attach the sticker to the vial.
  • Put the unused mixture in the refrigerator right away. Do not mix the contents of one vial with another vial.
  • Throw away any unused medicine after 14 days.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (prefilled syringe, prefilled autoinjector, or vial):
    • For juvenile idiopathic arthritis:
      • Children 2 years of age and older weighing 63 kilograms (kg) or more—50 milligrams (mg) injected under the skin once a week.
      • Children 2 years of age and older weighing less than 63 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The dose is 0.8 milligram (mg) per kilogram (kg) of body weight up to 50 mg, injected under the skin once a week.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
    • For plaque psoriasis:
      • Adults—At first, 50 milligrams (mg) injected under the skin two times per week, given 3 or 4 days apart, for 3 months. Then, your dose will be reduced to 50 mg once a week.
      • Children—Use and dose must be determined by your doctor.
    • For rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis:
      • Adults—50 milligrams (mg) injected under the skin once a week.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect the medicine from direct light. Keep your medicine in the original package until you are ready to use it.