Proper Use

Drug information provided by: Micromedex

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

This medicine should only be used in the nose.

Your doctor may limit the amount of fluid or water you drink. Follow the instructions carefully to prevent unwanted effects.

To use the nasal spray:

  • When used for the first time, the spray must be primed. Press the pump down 4 times. If the spray is not used for 1 week, prime the pump again by pressing once.
  • Gently blow your nose before using the spray. Tilt your head back slightly and insert the tip of the nose piece into your nostril.
  • Close the opposite nostril with a finger. Release one spray and breathe in gently at the same time.
  • Hold your breath for a few seconds then breathe out slowly through the mouth.
  • If a second dose is needed, spray the opposite nostril using the same steps.
  • Do not blow your nose or tip your head back after using the spray.
  • Wipe the tip of the bottle with a clean, dry tissue and replace the cap.
  • Throw away any unused medicine after 25 sprays (Stimate®) or 50 sprays (DDAVP® or desmopressin generic).

To use the DDAVP® Rhinal Tube nasal system:

  • The rhinal tube applicator is a soft, flexible plastic tube with numbers printed on the side. The numbers represent the dose.
  • Place the correct amount of medicine in the tube by inserting the tip of the container in the end of the tube that is marked with an arrow.
  • Put the end of the tube that is marked with an arrow into one nostril and put the other end into your mouth.
  • Hold your breath, tilt the head back, and blow with a short, strong puff until all the medicine is sprayed into the nose.
  • Do not let medicine run into your throat.
  • For young children, an adult must blow the medicine into the nose.
  • Wash the tube with water and shake it to remove all of the water.
  • Put the seal back on the container tip and replace the plastic cap.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For nasal dosage form (nasal spray):
    • For treatment of diabetes insipidus:
      • Adults and teenagers—0.1 to 0.4 milliliter (mL) given as a single dose or divided into 2 or 3 doses per day. The dose is given in one nostril or divided and given in both nostrils. Your doctor may adjust the dose as needed.
      • Children 3 months to 12 years of age—0.05 to 0.3 mL given as a single dose or divided into 2 doses per day. The dose is given in one nostril or divided and given in both nostrils. Your doctor may adjust the dose as needed.
      • Children younger than 3 months of age—Use and dose must be determined by your doctor.
    • For treatment of hemophilia A or won Willebrand disease:
      • Adults and teenagers—One spray (0.1 milliliter) in each nostril as a single dose per day. Your doctor may adjust the dose as needed.
      • Children 11 months to 12 years of age—Use and dose must be determined by your doctor.
      • Children younger than 11 months of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

DDAVP® or desmopressin generic: Store at room temperature in an upright position.

DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. For travelers, the product is good for up to 3 weeks at room temperature.

Stimate®: Store at room temperature in an upright position. Throw bottle away 6 months after it is used for the first time.