Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have chest tightness, cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, skin rash, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, trouble breathing, or unusual tiredness or weakness.

Apremilast may cause severe diarrhea, nausea, or vomiting which is more likely in patients 65 years of age or older, or in patients with low blood pressure (hypotension) or low blood volume (hypovolemia). Talk to your provider if you have concerns.

This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. Make sure your provider knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell your provider if you have sudden or strong feelings, including feeling nervous, angry, restless, violent, or scared. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.

This medicine may decrease your child's weight and height. You may need to check your child's weight and height regularly during treatment with this medicine. Talk to your child's doctor about ways to prevent weight loss.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.