Proper Use

Drug information provided by: Merative, Micromedex®

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take the medicine with food at about the same time each day.

Swallow the tablet whole. Do not crush, break, or chew it. Do not take this medicine if it is broken, cracked, or damaged.

If you cannot swallow Vijoice® tablets:

  • Mix the tablets into a glass with 2 to 4 ounces of water and let it stand for at least 5 minutes. Use water only.
  • Crush the tablets with a spoon and stir to dissolve. The mixture will be cloudy and you may still see some tablet pieces.
  • Swallow the mixture right away.
  • Add 2 to 3 tablespoons of water to the same glass and stir with the same spoon. Swallow the entire contents of the glass to make sure you get the full dose. Repeat this step if needed.

If you are using the Vijoice® oral granules:

  • Each packet is for single use only. Do not use the packet if the packet seal is broken.
  • Do not use multiple packets of the oral granules or part of a packet to prepare a dose. Do not combine the tablet with the granules.
  • Hold the packet of granules with the cut line on top. Shake the packet gently to make sure the granules are in the lower part of the packet. Open the packet along the cut line using scissors.
  • You may take the granules in one of the following ways:
    • Option 1: Pour the granules directly onto the tongue by tapping the side and top of the packet swallow it with about 4 to 8 tablespoons (2 to 4 ounces) of water. If there is any medicine remaining in the mouth, rinse the mouth with additional water and swallow to make sure the entire dose is taken.
    • Option 2: Pour the granules into a cup by tapping the side and top of the packet. Add 1 to 3 teaspoons (0.5 ounces) of liquid (including water, milk, or apple juice) or soft food (applesauce or yogurt). Take the mixture right away. Rinse the cup with up to 4 tablespoons (2 ounces) of water, milk or apple juice. Take the mixture right away. Repeat this step until there is no medicine left in the cup to make sure the entire dose is taken. Throw away any mixture that is not taken within 2 hours after preparing.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (granules and tablets):
    • For breast cancer:
      • Adults—300 milligrams (mg) (two 150 mg tablets) once a day. Your doctor may adjust your dose as needed and tolerated.
      • Children—Use and dose must be determined by your doctor.
    • For PIK3CA-related overgrowth spectrum (PROS):
      • Adults—250 milligrams (mg) once a day. Your doctor may adjust your dose as needed and tolerated.
      • Children 6 years of age and older—At first, 50 mg once a day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 125 mg once a day.
      • Children 2 to younger than 6 years of age—50 mg once a day. Your doctor may adjust your dose as needed and tolerated.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine and it is within 9 hours after the usual time, take it as soon as you can. Then go back to your regular schedule. If you miss a dose and it is more than 9 hours since your usual time, skip the missed dose and go back to your regular dosing schedule.

If you vomit after you take this medicine, do not take another dose the same day. Wait and take your next dose when you normally would.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away any unused mixture of Vijoice® after 60 minutes of mixing it.