Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Body aches or pain
  2. cough
  3. ear congestion
  4. gas with stomach pain
  5. hoarseness
  6. lightheadedness
  7. loss of voice
  8. lower back or side pain
  9. muscle aches and pains
  10. pain or tenderness around the eyes or cheekbones
  11. rapid and sometimes shallow breathing
  12. shivering
  13. stomach fullness
  14. stuffy nose
  15. sunken eyes
  16. thirst
  17. trouble sleeping
  18. warmth on the skin
  19. wrinkled skin

Less common

  1. Abnormal vaginal bleeding or discharge
  2. agitation
  3. arm, back, or jaw pain
  4. black, tarry stools
  5. bleeding from the gums or nose
  6. blindness
  7. bloating or swelling of the face, arms, hands, lower legs, or feet
  8. blood in the stool or change in bowel habits
  9. bloody or cloudy urine
  10. blurred vision
  11. broken bones
  12. change in size, shape, or color of an existing mole
  13. change in skin color
  14. chest pain, tightness, or heaviness
  15. chills
  16. clear or bloody discharge from the nipple
  17. cold hands and feet
  18. confusion
  19. constipation
  20. cough
  21. coughing or spitting up blood
  22. decreased urination
  23. decreased vision
  24. depression
  25. difficulty with breathing
  26. difficulty, burning, or painful urination
  27. dimpling of the breast skin
  28. dizziness
  29. drowsiness
  30. eye pain
  31. fainting
  32. fast, slow, or irregular heartbeat
  33. fever
  34. forgetfulness
  35. frequent urge to urinate
  36. general feeling of illness
  37. hair loss
  38. headache
  39. hives, itching, skin rash
  40. increased thirst
  41. inverted nipple
  42. irregular breathing
  43. irregular pulse
  44. irritability
  45. light colored stools
  46. loss of appetite
  47. lump in the breast or under your arm
  48. lump or swelling in the stomach
  49. mole that leaks fluid or bleeds
  50. muscle cramps or spasms
  51. nausea
  52. new mole
  53. night sweats
  54. no blood pressure or pulse
  55. noisy breathing
  56. numbness or tingling in your arms, legs, or face
  57. pain, redness, or swelling in the arms or legs without any injury present
  58. pale skin
  59. persistent non-healing sore on your skin
  60. pink growth
  61. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  62. raised, firm, or bright red patch
  63. redness or swelling of the breast
  64. seeing or hearing things that are not there
  65. seizures
  66. sharp back pain just below your ribs
  67. shiny bump on your skin
  68. slurred speech or problems with swallowing
  69. sneezing
  70. sore on the skin of the breast that does not heal
  71. sore throat
  72. sores, ulcers, or white spots on the lips or mouth
  73. spitting up blood
  74. stiff neck
  75. stomach pain
  76. stopping of the heart
  77. sudden high fever or low grade fever for months
  78. sweating
  79. swelling of the face, fingers, feet, or lower legs
  80. swollen glands
  81. swollen neck veins
  82. tiredness
  83. trouble breathing
  84. trouble thinking
  85. unconsciousness
  86. unexplained bruising or bleeding
  87. unpleasant breath odor
  88. unusual tiredness or weakness
  89. unusual weight gain or loss
  90. visual disturbances
  91. vomiting
  92. vomiting of blood or material that looks like coffee grounds
  93. yellow skin or eyes

Incidence not known

  1. Blistering, peeling, or loosening of the skin
  2. diarrhea
  3. inability to move the arms and legs
  4. joint or muscle pain
  5. pinpoint red spots on the skin
  6. red skin lesions, often with a purple center
  7. red, irritated eyes
  8. red, scaling, or crusted skin
  9. sudden numbness and weakness in the arms and legs
  10. unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Bladder pain
  2. bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  3. pounding in the ears

Less common

  1. Abnormal healing
  2. decrease in height
  3. difficulty with moving
  4. difficulty with walking
  5. dry mouth
  6. heartburn
  7. indigestion
  8. loss of hearing
  9. loss of strength or energy
  10. menstrual changes
  11. muscle or joint stiffness, tightness, or rigidity
  12. muscle pain or weakness
  13. pain in the back, ribs, arms, or legs
  14. shakiness in the legs, arms, hands, and feet
  15. swelling or redness in the joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.