Although your body may harbor the bacteria that cause tuberculosis, your immune system usually can prevent you from becoming sick. For this reason, doctors make a distinction between:
- Latent TB. In this condition, you have a TB infection, but the bacteria remain in your body in an inactive state and cause no symptoms. Latent TB, also called inactive TB or TB infection, isn't contagious. However, it can turn into active TB, so treatment is important for the person with latent TB and to help control the spread of TB in general. An estimated one-third of the world's population has latent TB.
- Active TB. This condition makes you sick and can spread to others. It can occur in the first few weeks after infection with the TB bacteria, or it might occur years later.
Signs and symptoms of active TB include:
- Unintentional weight loss
- Night sweats
- Loss of appetite
What organs are affected?
Tuberculosis usually attacks your lungs. Signs and symptoms of TB of the lungs include:
- Coughing that lasts three or more weeks
- Coughing up blood or sputum
- Chest pain, or pain with breathing or coughing
Tuberculosis can also affect other parts of your body, including your kidneys, spine or brain. When TB occurs outside your lungs, signs and symptoms vary according to the organs involved. For example, tuberculosis of the spine may give you back pain, and tuberculosis in your kidneys might cause blood in your urine.
When to see a doctor
See your doctor if you have a fever, unexplained weight loss, drenching night sweats or a persistent cough. These are often signs of TB, but they can also result from other medical problems. Your doctor can perform tests to help determine the cause.
Jan. 26, 2013
- Questions and answers about tuberculosis. Centers for Disease Control and Prevention. http://www.cdc.gov/tb/publications/faqs/pdfs/qa.pdf. Accessed Oct. 16, 2012.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Oct. 16, 2012.
- Sterling TR, et al. Three months of rifapentine and isoniazid for latent tuberculosis infection. New England Journal of Medicine. 2011;365:2155.
- Druszczynska M, et al. Latent M. tuberculosis infection - pathogenesis, diagnosis, treatment and prevention strategies. Polish Journal of Microbiology. 2012;61:3.
- Coussens AK, et al. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proceedings of the National Academy of Sciences. 2012;109:15449.
- Lawn SD, et al. Tuberculosis in antiretroviral treatment services in resource-limited settings: Addressing the challenges of screening and diagnosis. Journal of Infectious Diseases. 2011;204:S1159.
- Tuberculosis. World Health Organization. http://www.who.int/mediacentre/factsheets/fs104/en/index.html. Accessed Oct.23, 2012.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Oct. 16, 2012.
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