Overview

Tetralogy of Fallot (teh-TRAL-uh-jee of fuh-LOW) is a rare condition caused by a combination of four heart defects that are present at birth (congenital).

These defects, which affect the structure of the heart, cause oxygen-poor blood to flow out of the heart and to the rest of the body. Infants and children with tetralogy of Fallot usually have blue-tinged skin because their blood doesn't carry enough oxygen.

Tetralogy of Fallot is often diagnosed during infancy or soon after. However, tetralogy of Fallot might not be detected until later in life in some adults, depending on the severity of the defects and symptoms.

With early diagnosis followed by appropriate surgical treatment, most children and adults who have tetralogy of Fallot live relatively normal lives, though they'll need regular medical care throughout life and might have restrictions on exercise.

Tetralogy of Fallot care at Mayo Clinic

Aug. 26, 2017
References
  1. What is tetralogy of Fallot? National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/health-topics/topics/tof. Accessed April 6, 2017.
  2. Doyle T, et al. Pathophysiology, clinical features, and diagnosis of tetralogy of Fallot. https://www.uptodate.com/home. Accessed April 6, 2017.
  3. Doyle T, et al. Management and outcome of tetralogy of Fallot. https://www.uptodate.com/home. Accessed April 6, 2017.
  4. Facts about tetralogy of Fallot. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/heartdefects/TetralogyOfFallot.html. Accessed April 6, 2017.
  5. Tetralogy of Fallot. Merck Manual Professional Version. http://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/tetralogy-of-fallot. Accessed April 6, 2017.
  6. Bonow RO, et al., eds. Congenital heart disease. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2015. https://www.clinicalkey.com. Accessed April 6, 2017.
  7. Tetralogy of Fallot. American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Tetralogy-of-Fallot_UCM_307038_Article.jsp#.WQNyM9jrvcs. Accessed April 6, 2017.
  8. Finding support. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/birthdefects/families-support.html. Accessed May 8, 2017.
  9. How should I care for myself, as a caregiver? American Heart Association. http://www.heart.org/HEARTORG/Support/Resources-For-Caregivers_UCM_301850_Article.jsp#.WRCdTty1tpg. Accessed May 8, 2017.
  10. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. April 24, 2017.
  11. Connolly HM (expert opinion). Mayo Clinic, Rochester, Minn. May 19, 2017.

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