In most cases, it's not clear what causes soft tissue sarcoma.
In general, cancer occurs when cells develop errors (mutations) in their DNA. The errors make cells grow and divide out of control. The accumulating abnormal cells form a tumor that can grow to invade nearby structures and spread to other parts of the body.
The type of cell that develops the genetic mutation determines what type of soft tissue sarcoma you have. Some types of soft tissue sarcoma include:
Jan. 24, 2015
- Alveolar soft part sarcoma
- Clear cell sarcoma
- Dermatofibrosarcoma protuberans
- Desmoplastic small round cell tumor
- Epithelioid hemangioendothelioma
- Epithelioid sarcoma
- Extrarenal rhabdoid tumor
- Gastrointestinal stromal tumor
- Infantile fibrosarcoma
- Inflammatory myofibroblastic tumor
- Kaposi's sarcoma
- Malignant fibrous histiocytoma
- Malignant peripheral nerve sheath tumor
- PEComa (neoplasm with perivascular epithelioid cell differentiation)
- Synovial sarcoma
- Townsend CM Jr, et al. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. https://www.clinicalkey.com. Accessed July 19, 2013.
- Soft tissue sarcoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed July 24, 2013.
- Adult soft tissue sarcoma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/patient. Accessed July 19, 2013.
- Childhood soft tissue sarcoma treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/child-soft-tissue-sarcoma/Patient. Accessed July 19, 2013.
- Taking time: Support for people with cancer. National Cancer Institute. http://cancer.gov/cancertopics/takingtime. Accessed July 24, 2013.
- Golden AK. Decision Support System. Mayo Clinic, Rochester, Minn. Aug. 16, 2013.
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