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In most cases, it's not clear what causes soft tissue sarcoma.

In general, cancer occurs when cells develop errors (mutations) in their DNA. The errors make cells grow and divide out of control. The accumulating abnormal cells form a tumor that can grow to invade nearby structures and spread to other parts of the body.

The type of cell that develops the genetic mutation determines what type of soft tissue sarcoma you have. Some types of soft tissue sarcoma include:

  • Alveolar soft part sarcoma
  • Angiosarcoma
  • Clear cell sarcoma
  • Dermatofibrosarcoma protuberans
  • Desmoplastic small round cell tumor
  • Epithelioid hemangioendothelioma
  • Epithelioid sarcoma
  • Extrarenal rhabdoid tumor
  • Fibrosarcoma
  • Gastrointestinal stromal tumor
  • Hemangiosarcoma
  • Infantile fibrosarcoma
  • Inflammatory myofibroblastic tumor
  • Kaposi's sarcoma
  • Leiomyosarcoma
  • Liposarcoma
  • Lymphangiosarcoma
  • Malignant fibrous histiocytoma
  • Malignant peripheral nerve sheath tumor
  • Myofibrosarcoma
  • Myxofibrosarcoma
  • Neurofibrosarcoma
  • Perivascular epitheliod cell tumor (PEComa)
  • Rhabdomyosarcoma
  • Synovial sarcoma
  • Undifferentiated, unclassified soft tissue sarcomas
July 01, 2015