Sick sinus syndrome — also known as sinus node disease or sinus node dysfunction — is the name for a group of heart rhythm problems (arrhythmias) in which the sinus node — the heart's natural pacemaker — doesn't work properly.
The sinus node is an area of specialized cells in the upper right chamber of the heart that controls the rhythm of your heart. Normally, the sinus node produces a steady pace of regular electrical impulses. In sick sinus syndrome, these signals are abnormally paced.
A person with sick sinus syndrome may have heart rhythms that are too fast, too slow, punctuated by long pauses — or an alternating combination of all of these rhythm problems. Sick sinus syndrome is relatively uncommon, but the risk of developing sick sinus syndrome increases with age.
Many people with sick sinus syndrome eventually need a pacemaker to keep the heart in a regular rhythm.
May. 13, 2014
- Zipes DP, et al. Cardiac Elecrophysiology: From Cell to Bedside. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed Jan. 8, 2014.
- Sinus node dysfunction. The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/cardiovascular_disorders/arrhythmias_and_conduction_disorders/sinus_node_dysfunction.html. Accessed Jan. 8, 2014.
- Lau CP, et al. Prospective randomized study to assess the efficacy of site and rate of atrial pacing on long-term progression of atrial fibrillation in sick sinus syndrome: Septal pacing for atrial fibrillation suppression evaluation (SAFE) study. Circulation. 2013;128:687.
- Cheng A. Diagnosis and evaluation of the sick sinus syndrome. http://www.uptodate.com/home. Accessed Jan. 8, 2014.
- Cheng A. Manifestations and causes of the sick sinus syndrome. http://www.uptodate.com/home. Accessed Jan. 8, 2014.
- Semelka M, et al. Sick sinus syndrome: A review. American Family Physician. 2013;87:691.
- What is a pacemaker? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/pace/. Accessed Jan. 8, 2014.
- Tracy CM, et al. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities. Journal of the American College of Cardiology. 2013;61:e6.
- Non-surgical procedures for atrial fibrillation (Fib or AF). American Heart Association. http://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/Non-surgical-Procedures-for-Atrial-Fibrillation-Fib-or-AF_UCM_423782_Article.jsp. Accessed Jan. 8, 2014.
- Your guide to a healthy heart. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/public/heart/other/your_guide/yg_hh.htm. Accessed Jan. 8, 2014.
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