A blighted ovum, also called an anembryonic pregnancy or anembryonic gestation, occurs when a gestational sac develops without an embryo — often due to chromosomal abnormalities in the fertilized egg.
A blighted ovum usually occurs in the first few weeks of pregnancy, often before a woman even knows she's pregnant. However, a woman might miss a period and have a positive pregnancy test. This is because the placenta secretes human chorionic gonadotropin (HCG), a pregnancy hormone. Symptoms of early pregnancy — such as breast tenderness — are possible as well. But when the placenta stops growing and hormone levels decrease, the pregnancy symptoms subside. At this point, minor abdominal cramping and light spotting or bleeding are possible. An ultrasound will show an empty gestational sac.
A blighted ovum eventually results in miscarriage. Some women choose to wait for the miscarriage to happen naturally, while others take medication to trigger the miscarriage. In some cases, a procedure called dilation and curettage (D&C) is used to remove the placental tissues.
Most women who've had a blighted ovum go on to have successful pregnancies. If you experience multiple consecutive miscarriages, you might consider testing to identify any underlying causes.
Aug. 23, 2013
- Gabbe SG, et al. Obstetrics: Normal and Problem Pregnancies. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/208746819-4/0/1528/0.html. Accessed May 10, 2013.
- DeCherney AH, et al. Current Diagnosis & Treatment Obstetrics & Gynecology. 11th ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/content.aspx?aID=56965770. Accessed May 10, 2013.
- Prine LW, et al. Office management of early pregnancy loss. American Family Physician. 2011;84:75.
- Tulandi T, et al. Spontaneous abortion: Risk factors, etiology, clinical manifestations, and diagnostic evaluation. http://www.uptodate.com/home. Accessed May 10, 2013.
- Patient's fact sheet: Recurrent pregnancy loss. American Society for Reproductive Medicine. http://www.asrm.org/Recurrent_Pregnancy_Loss/. Accessed May 10, 2013.
- Gibbs RS, et al. Danforth's Obstetrics and Gynecology. 10th ed. Philadelphia, Pa.: Wolters Kluwer Health Lippincott Williams & Wilkins; 2008. http://www.danforthsobgyn.com. Accessed May 10, 2013.
- American College of Obstetricians and Gynecologists. Your Pregnancy and Childbirth Month to Month. 5th ed. Washington, D.C.: American College of Obstetricians and Gynecologists; 2010:1.
- Bastian LA, et al. Clinical manifestations and diagnosis of an early pregnancy. http://www.uptodate.com/home. Accessed May 10, 2013.