Primary progressive aphasia (uh-FAY-zhuh) is a rare nervous system (neurological) syndrome that affects your ability to communicate. People with primary progressive aphasia can have trouble expressing their thoughts and understanding or finding words.
Symptoms begin gradually, often before age 65, and worsen over time. People with primary progressive aphasia can lose the ability to speak and write, and, eventually, to understand written or spoken language.
People with this condition may continue caring for themselves and participating in daily life activities for several years after the disorder's onset because it progresses slowly.
Primary progressive aphasia is a type of frontotemporal degeneration, a cluster of related disorders that originate in the frontal or temporal lobes of the brain.
Primary progressive aphasia care at Mayo Clinic
Aug. 08, 2017
- Primary progressive aphasia. National Aphasia Association. http://www.aphasia.org/aphasia-resources/primary-progressive-aphasia/. Accessed Oct. 18, 2015.
- Lee SE, et al. Frontotemporal dementia: Clinical features and diagnosis. http://www.uptodate.com/home. Accessed Oct. 18, 2015.
- Leger GC, et al. A review on primary progressive aphasia. Neuropsychiatric Disease and Treatment. 2007;3:745.
- Kirshner HS. Frontotemporal dementia and primary progressive aphasia, a review. Neuropsychiatric Disease and Treatment. 2014;10:1045.
- Mesulam M, et al. Primary progressive aphasia and the evolving neurology of the language network. Nature Reviews Neurology. 2014;10:554.
- Rogalski EJ, et al. Association between the prevalence of learning disabilities and primary progressive aphasia. JAMA Neurology. 2014;71:1576.
- Masulam M. Primary progressive aphasia. Dementia & Neuropsychologia. 2013;7:2.
- Family adjustment to aphasia. American Speech-Language-Hearing Association. http://www.asha.org/public/speech/disorders/FamilyAdjustmentAphasia/. Accessed Oct. 20, 2015.
Primary progressive aphasia