Signs and symptoms of premature ovarian failure are similar to those experienced by a woman going through menopause and are typical of estrogen deficiency. They include:
- Irregular or skipped periods (amenorrhea), which may be present for years or may develop after a pregnancy or after stopping birth control pills
- Hot flashes
- Night sweats
- Vaginal dryness
- Irritability or difficulty concentrating
- Decreased sexual desire
When to see a doctor
If you notice that you've skipped your period for three months or more, see your doctor to help determine what may be the cause. You may miss your period for a number of reasons — including pregnancy, stress, or a change in diet or exercise habits — but it's best to get evaluated whenever your menstrual cycle changes.
Even if you don't mind that your periods have stopped, it's still wise to see your doctor and try to find out what's causing the problem. If your estrogen levels are low, bone loss can occur.
Feb. 12, 2014
- Shelling AN. Premature ovarian failure. Reproduction. 2010;140:633.
- Nelson LM, et al. Clinical manifestations and evaluation of spontaneous primary ovarian insufficiency (premature ovarian failure). http://www.uptodate.com/home. Accessed Aug. 27, 2013.
- Lentz GM, et al. Comprehensive Gynecology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.clinicalkey.com. Accessed Aug. 27, 2013.
- Welt CK. Pathogenesis and causes of spontaneous primary ovarian insufficiency (premature ovarian failure). http://www.uptodate.com/home. Accessed Aug. 27, 2013.
- Rafique S, et al. A new approach to primary ovarian insufficiency. Obstetrics & Gynecology Clinics of North America. 2012;39:567.
- Nelson LM, et al. Management of spontaneous primary ovarian insufficiency (premature ovarian failure). http://www.uptodate.com/home. Accessed Aug. 27, 2013.
- Ross AC, et al. Dietary reference intakes for calcium and vitamin D. Institute of Medicine. http://www.nap.edu/openbook.php?record_id=13050&page=1. Accessed Aug. 26, 2013.
- Coddington CC (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 16, 2013.
- Questions and answers about estrogen-plus-progestin hormone therapy. Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/women/q_a.htm. Accessed Sept. 5, 2013.
- Schierbeck LL, et al. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: Randomised trial. BMJ. 2012;345:e6409.