Peyronie's disease signs and symptoms might appear suddenly or develop gradually. The most common signs and symptoms include:
- Scar tissue. The scar tissue (plaques) associated with Peyronie's disease can be felt under the skin of the penis as flat lumps or a band of hard tissue.
- A significant bend to the penis. Your penis might be curved upward, downward or bent to one side. In some cases, the erect penis might have narrowing, indentations or an hourglass appearance, with a tight, narrow band around the shaft.
- Erection problems. Peyronie's disease might cause problems getting or maintaining an erection (erectile dysfunction).
- Shortening of the penis. Your penis might become shorter as a result of Peyronie's disease.
- Pain. You might have penile pain, with or without an erection.
The curvature associated with Peyronie's disease might gradually worsen. At some point, however, it stabilizes in the majority of men.
In most men, pain during erections improves within one to two years, but the scar tissue and curvature often remain. For a few men, both the curvature and pain associated with Peyronie's disease improve without treatment.
When to see a doctor
See your doctor if pain or curvature of your penis prevents you from having sex or causes you anxiety.
Oct. 18, 2014
- Hatzimouratidis K, et al. EAU guidelines on penile curvature. European Urology. 2012;62:543.
- Wein AJ, et al. Campbell-Walsh Urology. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed May 11, 2014.
- Brandt WO, et al. Peyronie's disease: Diagnosis and medical management. http://www.uptodate.com/home. Accessed May 11, 2014.
- Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2014. https://www.clinicalkey.com. Accessed May 11, 2014.
- Peyronie's disease. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/peyronie. Accessed May 11, 2014.
- Brandt WO, et al. Surgical management of Peyronie's disease. http://www.uptodate.com/home. Accessed May 11, 2014.
- Golden AK. Decision Support System. Mayo Clinic, Rochester, Minn. April 23, 2014.
- FDA approves first drug for treatment of Peyronie's disease. U.S. Food and Drug Administration. http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm377849.htm. Accessed May 11, 2014.
- Trost LW (expert opinion). Mayo Clinic, Rochester, Minn. May 28, 2014.
- Broderick GA (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 11, 2014.
- Xiaflex (prescribing information). Chesterbrook, Penn.: Auxilium Pharmaceuticals, Inc.; 2013. https://www.xiaflex.com/assets/XIAFLEX-PI-and-MedGuide-Combined-20131206-ver-e.pdf. Accessed Sept. 15, 2014.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.