Risk factors

By Mayo Clinic Staff

Minor injury to the penis doesn't always lead to Peyronie's disease. However, various factors can contribute to poor wound healing and scar tissue buildup that might play a role in Peyronie's disease. These include:

  • Heredity. If your father or brother has Peyronie's disease, you have an increased risk of the condition.
  • Connective tissue disorders. Men who have a connective tissue disorder appear to have an increased risk of developing Peyronie's disease. For example, a number of men who have Peyronie's disease also have a condition known as Dupuytren's contracture — a cord-like thickening across the palm that causes the fingers to pull inward.
  • Age. The prevalence of Peyronie's disease increases with age. Age-related changes in tissues might cause them to be more easily injured and less likely to heal well.

Other factors — including certain health conditions, smoking and some types of prostate surgery — might be linked to Peyronie's disease.

Oct. 18, 2014