Scientists don't yet fully understand what causes nasal polyps. It's not clear why some people develop chronic inflammation or why ongoing inflammation triggers polyp formation in some people and not in others. The inflammation occurs in the fluid-producing lining (mucous membrane) of your nose and sinuses. There's some evidence that people who develop polyps have a different immune system response and different chemical markers in their mucous membranes than do those who don't develop polyps.
Nasal polyps can form at any age, but they're most common in young and middle-aged adults. Nasal polyps may form anywhere in your sinuses or nasal passages, but they appear most often in an area where sinuses near your eyes, nose and cheekbones all drain through winding passages into your nose (ostiomeatal complex).
March 08, 2014
- Nasal polyps. The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/ear_nose_and_throat_disorders/nose_and_paranasal_sinus_disorders/nasal_polyps.html. Accessed Oct. 15, 2013.
- Kalish L, et al. Topical steroids for nasal polyps. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006549.pub2/abstract. Accessed Oct. 15, 2013.
- DeMarcantonio MA, et al. Nasal polyps: Pathogenesis and treatment implications. Otolaryngologic Clinics of North America. 2011;44:685.
- Diagnosis and treatment of respiratory illness in children and adults. Institute for Clinical Systems Improvement. https://www.icsi.org/guidelines__more/catalog_guidelines_and_more/catalog_guidelines/catalog_respiratory_guidelines/respiratory_illness/. Accessed Oct. 15, 2013.
- Aring AM, et al. Acute rhinosinusitis in adults. American Family Physician. 2011;83:1057.
- Adkinson NF, et al. Middleton's Allergy: Principles and Practice. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. https://www.clinicalkey.com. Accessed Oct. 15, 2013.
- Bhattacharyya N. Clinical presentation, diagnosis, and treatment of nasal obstruction. http://www.uptodate.com/home. Accessed Oct. 15, 2013.
- Naegleria fowleri. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/naegleria/. Accessed Oct. 15, 2013.
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