Myelofibrosis usually develops slowly. In its very early stages, many people don't experience signs or symptoms. But as disruption of normal blood cell production increases, signs and symptoms may include:
- Feeling tired, weak or short of breath, usually because of anemia
- Pain or fullness below your ribs on the left side, due to an enlarged spleen
- Pale skin
- Easy bruising
- Easy bleeding
- Excessive sweating during sleep (night sweats)
- Frequent infections
- Bone pain
When to see a doctor
Make an appointment with your doctor if you have any persistent signs and symptoms that worry you.
Aug. 01, 2014
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- Myelofibrosis facts. Leukemia & Lymphoma Society. http://www.lls.org/#/diseaseinformation/myeloproliferativediseases/idiopathicmyelofibrosis. Accessed Sept. 23, 2013.
- Thorium. Agency for Toxic Substances and Disease Registry. http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=659&tid=121. Accessed Sept. 23, 2013.
- Jakafi (prescribing information). Wilmington, Del.: Incyte Corporation; 2013. http://www.jakafi.com. Accessed Sept. 23, 2013.
- Bone marrow transplantation and peripheral blood stem cell transplantation. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Therapy/bone-marrow-transplant. Accessed Sept. 25, 2013.
- Cook AJ. Decision Support System. Mayo Clinic, Rochester, Minn. July 5, 2013.
- Mesa RA (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. Sept. 26, 2013.
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