Treatment isn't necessary for most cases of morning sickness. If your morning sickness symptoms persist, however, your pregnancy care provider may prescribe vitamin B-6 supplements, antihistamines and possibly anti-nausea medications.
If you have severe morning sickness, your doctor might talk to you about medication to treat it. The combination of doxylamine and pyridoxine (Diclegis) has been approved by the Food and Drug Administration for treating nausea in pregnancy. Drowsiness can occur with this medicine, so it's important to avoid activities that require mental alertness, such as driving, when taking it.
If you have hyperemesis gravidarum, you may need to be treated with intravenous (IV) fluids and anti-nausea medications in the hospital.
Sept. 18, 2014
- Smith JA, et al. Treatment and outcomes of nausea and vomiting of pregnancy. http://www.uptodate.com/home. Accessed July. 10, 2014.
- American College of Obstetrics and Gynecology (ACOG) Committee on Practice Bulletins — Obstetrics. ACOG Practice Bulletin No. 52. Nausea and vomiting of pregnancy. Obstetrics and Gynecology. 2004;103:803.
- Frequently asked questions. Pregnancy FAQ126. Morning sickness. American College of Obstetricians and Gynecologists. http://www.acog.org/~/media/For%20Patients/faq126.pdf?dmc=1&ts=20140710T1203324342. Accessed July 10, 2014.
- AskMayoExpert. What medications can be used if lifestyle modification is not effective for nausea and vomiting in pregnancy? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
- Creasy RK, et al. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed July 10, 2014.
- Goodwin TM. Hyperemesis gravidarum. Obstetrics and Gynecology Clinics of North America. 2008;35:401.
- Ginger. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 17, 2014.
- Acupressure. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 17, 2014.
- Maltepe C, et al. The management of nausea and vomiting of pregnancy and hyperemesis gravidarum — a 2013 update. Journal of Population Therapeutics and Clinical Pharmacology. 2013;20:e184.
- Slaughter SR, et al. FDA approval of doxylamine-pyridoxine therapy for use in pregnancy. New England Journal of Medicine. 2014;370:1081.
- Czeizel AE, et al. The effect of periconceptional multivitamin-mineral supplementation on vertigo, nausea and vomiting in the first trimester of pregnancy. Archives of Gynecology and Obstetrics. 1992;251:181.
- Emelianova S, et al. Prevalence and severity of nausea and vomiting of pregnancy and effect of vitamin supplementation. Clinical and Investigative Medicine. 1999;22:106.
- Gabbe SE, et al. Obstetrics: Normal and Problem Pregnancies. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed July 10, 2014.
- Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. July 10, 2014.
- Refruezo JS, et al. Clinical features and evaluation of nausea and vomiting of pregnancy. http://www.uptodate.com/home. Accessed July 10, 2014.
- Diclegis (prescribing information). Bryn Mawr, Penn.: Duchesnay Inc., 2013. http://www.diclegis.com/pdf/Diclegis_Full_Prescribing_Information.pdf. Accessed July 10, 2014.
- FDA approves Diclegis for pregnant women experiencing nausea and vomiting. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm347087.htm. Accessed July 10, 2014.
- Murry MM (expert opinion). Mayo Clinic, Rochester, Minn. July 27, 2014.
- Parisa Y, et al. The effect of lemon inhalation aromatherapy on nausea and vomiting of pregnancy: A double-blinded, randomized, controlled clinical trial. Iranian Red Crescent Medical Journal. 2014;16:e14360.
- Pasha H, et al. Study of the effect of mint oil on nausea and vomiting during pregnancy. Iranian Red Crescent Medical Journal. 2012;14:727.