Overview

Mitral valve prolapse (MVP) occurs when the leaflets of the mitral valve bulge (prolapse) into the heart's left upper chamber (left atrium) like a parachute during the heart's contraction.

Mitral (MY-trul) valve prolapse sometimes leads to blood leaking backward into the left atrium, a condition called mitral valve regurgitation.

In most people, mitral valve prolapse isn't life-threatening and doesn't require treatment or changes in lifestyle. Some people with mitral valve prolapse, however, require treatment.

Feb. 11, 2017
References
  1. Pislaru S, et al. Definition and diagnosis of mitral valve prolapse. http://www.uptodate.com/home. Accessed Nov. 23, 2016.
  2. What is mitral valve prolapse? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/mvp/. Accessed Nov. 23, 2016.
  3. Ferri FF. Mitral valve prolapse. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed Nov 23, 2016.
  4. Bope ET, et al. The cardiovascular system. In: Conn's Current Therapy 2016. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Nov. 23, 2016.
  5. Nishimura RA, et al. 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary. Journal of the American College of Cardiology. 2014;63:2438.
  6. American Heart Association. Problem: Mitral valve prolapse. http://www.heart.org/HEARTORG/Conditions/More/HeartValveProblemsandDisease/Problem-Mitral-Valve-Prolapse_UCM_450441_Article.jsp#.WDJJF9UrJ0w. Accessed Nov. 23, 2016.
  7. American Heart Association. Atrial fibrillation medications. http://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/Atrial-Fibrillation-Medications_UCM_423781_Article.jsp#.WDJKytUrJ0w. Accessed Nov. 23, 2016.
  8. American Heart Association. Warning signs of a heart attack. http://www.heart.org/HEARTORG/Conditions/HeartAttack/WarningSignsofaHeartAttack/Warning-Signs-of-a-Heart-Attack_UCM_002039_Article.jsp#.WDJNgtUrJ0w. Accessed Nov. 23, 2016.
  9. Shiota T. Role of echocardiography for catheter-based management of valvular heart disease. Journal of Cardiology. In press. Accessed Nov. 23, 2016.
  10. Mitral regurgitation (adult). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
  11. Mankad R (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 20, 2016.