At its earliest stages, invasive lobular carcinoma may cause no signs and symptoms. As it grows larger, invasive lobular carcinoma may cause:
- An area of thickening in part of the breast
- A new area of fullness or swelling in the breast
- A change in the texture or appearance of the skin over the breast, such as dimpling or thickening
- An inverted nipple
Invasive lobular carcinoma is less likely than other forms of breast cancer to cause a firm breast lump.
When to see a doctor
Make an appointment with your doctor if you have any signs or symptoms that worry you.
Ask your doctor when to begin screening tests for breast cancer. Routine screening tests may include a physical exam and breast X-rays (mammograms). Various organizations differ on their screening recommendations, but many suggest women with an average risk of breast cancer consider beginning yearly mammograms in their 40s. If you have a family history of breast cancer or other factors that increase your risk of breast cancer, your doctor may recommend beginning screening mammograms or other tests at an earlier age.
May. 22, 2012
- Rakha EA, et al. Lobular breast carcinoma and its variants. Seminars in Diagnostic Pathology. 2010;27:49.
- Chen WY. Postmenopausal hormone therapy and breast cancer risk: Current status and unanswered questions. Endocrinology and Metabolism Clinics of North America. 2011;40:509.
- Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-4/0/1709/0.html. Accessed April 24, 2012.
- Breast cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed April 24, 2012.
- Biglia N, et al. Increased incidence of lobular breast cancer in women treated with hormone replacement therapy: Implications for diagnosis, surgical and medical treatment. Endocrine-Related Cancer. 2007;14:549.
- Schrader KA, et al. Hereditary diffuse gastric cancer: Association with lobular breast cancer. Familial Cancer. 2008;7:73.
- Breast cancer treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/breast/healthprofessional. Accessed April 24, 2012.
- Breast cancer prevention (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/prevention/breast/healthprofessional. Accessed April 24, 2012.
- Avis NE. Breast cancer survivors and hot flashes: The search for nonhormonal treatments. Journal of Clinical Oncology. 2008;26:5008.
- Pruthi S (expert opinion). Mayo Clinic, Rochester, Minn. May 7, 2012.
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