Interstitial cystitis (in-tur-STISH-ul sis-TIE-tis) — also called painful bladder syndrome — is a chronic condition causing bladder pressure, bladder pain and sometimes pelvic pain. The pain ranges from mild discomfort to severe.
Your bladder is a hollow, muscular organ that stores urine. The bladder expands until it's full and then signals your brain that it's time to urinate, communicating through the pelvic nerves. This creates the urge to urinate for most people.
With interstitial cystitis, these signals get mixed up — you feel the need to urinate more often and with smaller volumes of urine than most people.
Interstitial cystitis most often affects women and can have a long-lasting impact on quality of life. Although there's no cure, medications and other therapies may offer relief.
Oct. 11, 2016
- Interstitial cystitis/painful bladder syndrome. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/interstitialcystitis/. Accessed July 1, 2016.
- Clemens JQ. Pathogenesis, clinical features, and diagnosis of interstitial cystitis/bladder pain syndrome. http://www.uptodate.com/home. Accessed July 1, 2016.
- Interstitial cystitis. Merck Manual Professional Version. http://www.merckmanuals.com/professional/genitourinary_disorders/voiding_disorders/interstitial_cystitis.html. Accessed July 1, 2016.
- Wein AJ, et al., eds. Bladder pain syndrome (interstitial cystitis) and related isorders. In: Campbell-Walsh Urology. 11th ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed July 1, 2016.
- Clemens JQ. Management of interstitial cystitis/bladder pain syndrome. http://www.uptodate.com/home. Accessed July 1, 2016.
- Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Linthicum, Md.: American Urological Association. http://www.auanet.org/education/guidelines/ic-bladder-pain-syndrome.cfm. Accessed July 1, 2016.
- Longo DL, et al., eds. Dysuria, bladder pain, and the interstitial cystitis/bladder pain syndrome. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: McGraw-Hill Education; 2015. http://www.accessmedicine.com. Accessed July 1, 2016.
- The urinary tract and how it works. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/health-topics/Anatomy/urinary-tract-how-it-works/Pages/anatomy.aspx. Accessed July 1, 2016.
- Castle EP (expert opinion). Mayo Clinic, Phoenix, Ariz. July 7, 2016.
- Pang R, et al. The Chinese approach to complementary and alternative medicine for interstitial cystitis/bladder pain syndrome. Translational Andrology and Urology. 2015;4:653.
- Carrico D, et al. Guided imagery for women with interstitial cystitis: results of a prospective, randomized controlled pilot study. The Journal of Alternative and Complementary Medicine. 2018;14:53.